Detailed information of TA system TA100688

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 3376522..3377544
• Replicon: chromosome
• Accession: NZ_CP028158
• Organism: Plantactinospora sp. BC1

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: C6361_RS14570
• Protein ID: WP_107268071.1
• Coordinates: 3376987..3377544 (+)
• Length: 186 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: C6361_RS14565
• Protein ID: WP_107268070.1
• Coordinates: 3376522..3376983 (+)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C6361_RS14540	3371614..3372789	-	1176	WP_107257924.1	sensor histidine kinase	-
C6361_RS14545	3372933..3373394	+	462	WP_107268068.1	ATP-binding protein	-
C6361_RS14550	3373450..3374970	+	1521	WP_107270958.1	glycerol kinase GlpK	-
C6361_RS14555	3374999..3375937	+	939	WP_107268069.1	phosphotransferase	-
C6361_RS14560	3375962..3376366	-	405	WP_107257921.1	MmcQ/YjbR family DNA-binding protein	-
C6361_RS14565	3376522..3376983	+	462	WP_107268070.1	helix-turn-helix domain-containing protein	Antitoxin
C6361_RS14570	3376987..3377544	+	558	WP_107268071.1	PIN domain-containing protein	Toxin
C6361_RS14575	3377716..3378255	-	540	WP_107257920.1	hypothetical protein	-
C6361_RS14580	3378408..3382214	+	3807	WP_107268072.1	PD40 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (10-111)

Antitoxin

• Helix-turn-helix domain, group 17 (84-131)

Sequences

Toxin

Protein

• Length: 186 a.a.
• Molecular weight: 20794.69 Da
• Isoelectric Point: 5.0768

>T100688 WP_107268071.1 NZ_CP028158:3376987-3377544 [Plantactinospora sp. BC1]
MTFVAVYDAGVLYPSTLRDLLIRIAQSGLVDAKWTEQILDEMFLALGRQRPELDQTRLARTRTLMGRAVRDWKITGYEPL
VDALKLPDPDDRHVLAAAIRARAQIIVTANLRHFPAEELRAWDIDPKSPDEFVRDQISLDRSTVYAAVQQIADSWRNPPG
SFDDVLDRLERSGLGVSVAELRAGG

Nucleotide

• Length: 558 bp

>T100688 NZ_CP028158:3376987-3377544 [Plantactinospora sp. BC1]
ATGACCTTCGTCGCCGTCTACGACGCCGGCGTGCTGTATCCGAGTACCCTGCGCGATCTACTGATTCGGATTGCCCAGTC
GGGTCTCGTCGATGCCAAGTGGACCGAGCAGATCCTCGACGAGATGTTCCTCGCTCTGGGCAGGCAGCGACCAGAGCTTG
ACCAGACCAGACTGGCCAGAACCCGGACCCTCATGGGAAGGGCCGTCCGAGACTGGAAGATCACTGGCTACGAGCCTCTC
GTCGACGCTCTCAAACTGCCCGACCCCGACGATCGCCACGTACTCGCCGCCGCCATCCGGGCGCGTGCCCAGATCATCGT
CACCGCCAACCTCCGACACTTCCCCGCCGAGGAGCTCCGCGCCTGGGACATAGATCCCAAGTCACCCGACGAATTCGTCC
GAGACCAGATAAGCCTGGACCGGAGCACGGTCTACGCGGCTGTGCAACAGATTGCCGATTCGTGGCGCAATCCCCCGGGT
AGCTTCGATGACGTGCTGGACCGCCTCGAACGATCCGGCCTCGGGGTCAGCGTCGCCGAACTGCGGGCGGGAGGATAA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 16864.22 Da
• Isoelectric Point: 6.2235

>AT100688 WP_107268070.1 NZ_CP028158:3376522-3376983 [Plantactinospora sp. BC1]
MIMNLAVNPVTPDPQSVEVAAEALTRVQAYLRTHQDDSATVRLVDDNEAEQLVVPRGAIELLARVLAHMANGHSVSVVPA
HAELTTQQAAQLLNVSRPYLIGLLEAGEIEYRKVGTHRRVLAGSLLAYKHRDDVRRRKAADELTQLAQEMDLT

Nucleotide

• Length: 462 bp

>AT100688 NZ_CP028158:3376522-3376983 [Plantactinospora sp. BC1]
ATGATCATGAACCTGGCCGTGAACCCGGTGACCCCGGACCCGCAATCGGTCGAAGTGGCTGCCGAAGCGCTCACCCGAGT
GCAGGCGTACCTCCGTACGCATCAGGACGACTCCGCCACCGTTCGACTGGTCGACGACAACGAGGCCGAACAGCTTGTCG
TACCCCGGGGAGCGATCGAACTGCTCGCCCGCGTTCTCGCACACATGGCGAATGGCCACAGCGTCTCGGTCGTTCCCGCT
CACGCGGAGCTGACGACCCAGCAGGCGGCCCAGCTGCTCAACGTGTCGAGGCCCTACCTGATCGGCCTACTGGAGGCCGG
CGAGATCGAGTACCGCAAGGTGGGGACGCACCGCCGCGTCCTCGCCGGTTCGCTTCTTGCGTACAAGCACCGAGATGACG
TTCGACGCCGGAAGGCCGCCGACGAGCTGACCCAACTGGCGCAAGAGATGGATCTGACCTGA