Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TsxAB/Xre(antitoxin) |
| Location | 17058..17559 | Replicon | plasmid pRM4283-2 |
| Accession | NZ_CP028155 | ||
| Organism | Salmonella enterica subsp. enterica serovar Enteritidis strain RM4283 | ||
Toxin (Protein)
| Gene name | TsxA | Uniprot ID | A0A6X6XTU7 |
| Locus tag | SEEERM4283_RS00120 | Protein ID | WP_000702245.1 |
| Coordinates | 17299..17559 (-) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | TsxB | Uniprot ID | - |
| Locus tag | SEEERM4283_RS00115 | Protein ID | WP_001132407.1 |
| Coordinates | 17058..17309 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SEEERM4283_RS00060 | 12122..12829 | + | 708 | WP_000108795.1 | hypothetical protein | - |
| SEEERM4283_RS00065 | 12849..13286 | + | 438 | WP_000206706.1 | hypothetical protein | - |
| SEEERM4283_RS00070 | 13292..13495 | + | 204 | WP_000224735.1 | hypothetical protein | - |
| SEEERM4283_RS00075 | 13497..14012 | + | 516 | WP_001229210.1 | hypothetical protein | - |
| SEEERM4283_RS00080 | 14009..14329 | + | 321 | WP_001401701.1 | hypothetical protein | - |
| SEEERM4283_RS00085 | 14459..14896 | - | 438 | WP_000466318.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| SEEERM4283_RS00090 | 14921..15103 | - | 183 | WP_000833470.1 | type II toxin-antitoxin system HicA family toxin | - |
| SEEERM4283_RS00095 | 15661..15843 | + | 183 | WP_001401700.1 | hypothetical protein | - |
| SEEERM4283_RS00100 | 16230..16508 | - | 279 | WP_000545937.1 | hypothetical protein | - |
| SEEERM4283_RS00115 | 17058..17309 | - | 252 | WP_001132407.1 | transcriptional regulator | Antitoxin |
| SEEERM4283_RS00120 | 17299..17559 | - | 261 | WP_000702245.1 | hypothetical protein | Toxin |
| SEEERM4283_RS00125 | 17611..17835 | - | 225 | WP_000814383.1 | hypothetical protein | - |
| SEEERM4283_RS00130 | 17933..18142 | - | 210 | WP_000866037.1 | hypothetical protein | - |
| SEEERM4283_RS00135 | 18183..18506 | - | 324 | WP_000427402.1 | hypothetical protein | - |
| SEEERM4283_RS00145 | 19087..19416 | - | 330 | WP_000855121.1 | hypothetical protein | - |
| SEEERM4283_RS00155 | 20014..20679 | + | 666 | WP_000532148.1 | P-loop NTPase | - |
| SEEERM4283_RS24745 | 20753..21037 | + | 285 | WP_001162371.1 | hypothetical protein | - |
| SEEERM4283_RS00165 | 21055..21651 | - | 597 | WP_000125165.1 | hypothetical protein | - |
| SEEERM4283_RS00170 | 21801..21962 | - | 162 | WP_001366886.1 | type I toxin-antitoxin system Hok family toxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..60014 | 60014 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 12822.38 Da Isoelectric Point: 5.5500
>T100686 WP_000702245.1 NZ_CP028155:c17559-17299 [Salmonella enterica subsp. enterica serovar Enteritidis]
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Download Length: 261 bp
>T100686 NZ_CP028155:c17559-17299 [Salmonella enterica subsp. enterica serovar Enteritidis]
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Antitoxin
Download Length: 84 a.a. Molecular weight: 12380.85 Da Isoelectric Point: 5.5500
>AT100686 WP_001132407.1 NZ_CP028155:c17309-17058 [Salmonella enterica subsp. enterica serovar Enteritidis]
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Download Length: 252 bp
>AT100686 NZ_CP028155:c17309-17058 [Salmonella enterica subsp. enterica serovar Enteritidis]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|