Detailed information of TA system TA100675

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 41410..41963
• Replicon: chromosome
• Accession: NZ_CP028137
• Organism: Rathayibacter festucae DSM 15932

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C1I64_RS00190
• Protein ID: WP_127885846.1
• Coordinates: 41682..41963 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C1I64_RS00185
• Protein ID: WP_127885845.1
• Coordinates: 41410..41685 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C1I64_RS00170	37244..38755	-	1512	WP_164874405.1	PucR family transcriptional regulator ligand-binding domain-containing protein	-
C1I64_RS00175	38861..40204	+	1344	WP_127885843.1	aspartate aminotransferase family protein	-
C1I64_RS00180	40508..41254	-	747	WP_127885844.1	ZIP family zinc transporter	-
C1I64_RS00185	41410..41685	+	276	WP_127885845.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
C1I64_RS00190	41682..41963	+	282	WP_127885846.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C1I64_RS00195	41975..42763	-	789	WP_127885847.1	endo alpha-1,4 polygalactosaminidase	-
C1I64_RS00200	42776..44050	+	1275	WP_127885848.1	VWA domain-containing protein	-
C1I64_RS00205	44047..44955	+	909	WP_127885849.1	FHA domain-containing protein	-
C1I64_RS00210	45358..46347	-	990	WP_127885850.1	serine/threonine protein kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (9-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10202.89 Da
• Isoelectric Point: 9.7249

>T100675 WP_127885846.1 NZ_CP028137:41682-41963 [Rathayibacter festucae DSM 15932]
VSPEPPFEVRFTSPAVRALHRLPPKLAEAVLRFCAEPLAENPLRVTKPLSAELAGLRSGYVGVAYRVLVAIDEEARVVSV
LRIGHRADIYGTR

Nucleotide

• Length: 282 bp

>T100675 NZ_CP028137:41682-41963 [Rathayibacter festucae DSM 15932]
GTGAGTCCGGAACCGCCCTTCGAGGTCCGGTTCACCAGTCCCGCCGTTCGAGCCCTGCACCGCCTGCCGCCGAAGCTGGC
CGAGGCGGTGCTCCGCTTCTGCGCCGAGCCCCTCGCCGAGAACCCCCTGCGCGTCACGAAGCCGCTGAGCGCGGAGCTCG
CGGGTCTGCGCTCCGGCTACGTCGGCGTGGCGTATCGCGTGCTGGTCGCCATCGACGAGGAGGCGCGAGTGGTGTCCGTC
CTGAGGATCGGGCATCGCGCCGACATCTACGGCACCCGCTAG

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9645.70 Da
• Isoelectric Point: 4.6216

>AT100675 WP_127885845.1 NZ_CP028137:41410-41685 [Rathayibacter festucae DSM 15932]
MQTLSVSEAKNHLSSLVDSVEATHDAVVITRHGKAAAVLISPDDLDSLTETIAWLSDPAHRGEIGEAESEVAAGRTLSLD
EVRAQLASRRA

Nucleotide

• Length: 276 bp

>AT100675 NZ_CP028137:41410-41685 [Rathayibacter festucae DSM 15932]
ATGCAGACTCTCTCGGTCAGTGAAGCGAAGAACCACCTCTCGTCCCTCGTCGACTCGGTGGAGGCGACCCACGACGCCGT
CGTGATCACGCGCCACGGCAAGGCGGCGGCGGTCCTCATCTCGCCGGACGACCTCGACTCGCTGACCGAGACCATCGCCT
GGCTCTCCGATCCGGCGCACCGGGGAGAGATCGGCGAGGCGGAGTCGGAGGTCGCAGCGGGTCGAACGCTGAGCCTCGAC
GAGGTCCGCGCGCAGCTGGCGAGTCGACGGGCGTGA