100666

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4485167..4485528 Replicon chromosome
Accession NZ_CP028127
Organism Xanthomonas vasicola pv. vasculorum strain SAM119

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag C7V42_RS20475 Protein ID WP_010374872.1
Coordinates 4485167..4485301 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag C7V42_RS20480 Protein ID WP_010374875.1
Coordinates 4485376..4485528 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7V42_RS20460 4482191..4483249 - 1059 WP_026112172.1 MBL fold metallo-hydrolase -
C7V42_RS20465 4483265..4484554 - 1290 WP_010374868.1 tryptophan--tRNA ligase -
C7V42_RS20470 4484726..4484935 - 210 WP_017117799.1 CsbD family protein -
C7V42_RS20475 4485167..4485301 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
C7V42_RS20480 4485376..4485528 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
C7V42_RS20485 4485636..4486559 - 924 WP_010379236.1 arginase -
C7V42_RS20490 4486882..4487334 + 453 WP_010374879.1 roadblock/LC7 domain-containing protein -
C7V42_RS20495 4487398..4487757 + 360 WP_010374881.1 hypothetical protein -
C7V42_RS20500 4487855..4488772 + 918 WP_017112292.1 hypothetical protein -
C7V42_RS20505 4488769..4489311 + 543 WP_010374885.1 GTPase -
C7V42_RS20515 4489790..4490473 + 684 WP_010374890.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T100666 WP_010374872.1 NZ_CP028127:c4485301-4485167 [Xanthomonas vasicola pv. vasculorum]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T100666 NZ_CP028127:c4485301-4485167 [Xanthomonas vasicola pv. vasculorum]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT100666 WP_010374875.1 NZ_CP028127:c4485528-4485376 [Xanthomonas vasicola pv. vasculorum]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT100666 NZ_CP028127:c4485528-4485376 [Xanthomonas vasicola pv. vasculorum]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References