Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1280063..1280562 Replicon chromosome
Accession NZ_CP028127
Organism Xanthomonas vasicola pv. vasculorum strain SAM119

Toxin (Protein)


Gene name relE Uniprot ID A0A7C7F2G6
Locus tag C7V42_RS05990 Protein ID WP_010368415.1
Coordinates 1280063..1280314 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A836ZTX6
Locus tag C7V42_RS05995 Protein ID WP_010368416.1
Coordinates 1280311..1280562 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7V42_RS05965 1275711..1277066 + 1356 WP_017112158.1 aminodeoxychorismate synthase component I -
C7V42_RS05970 1277127..1278200 + 1074 WP_010368412.1 endolytic transglycosylase MltG -
C7V42_RS05975 1278197..1279156 + 960 WP_010368413.1 DNA polymerase III subunit delta' -
C7V42_RS05980 1279153..1279506 + 354 WP_003483889.1 PilZ domain-containing protein -
C7V42_RS05990 1280063..1280314 - 252 WP_010368415.1 Txe/YoeB family addiction module toxin Toxin
C7V42_RS05995 1280311..1280562 - 252 WP_010368416.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C7V42_RS06000 1280744..1281070 + 327 WP_010368417.1 hypothetical protein -
C7V42_RS06005 1281331..1282932 - 1602 WP_010368418.1 propionate catabolism operon regulatory protein PrpR -
C7V42_RS06010 1283078..1283974 + 897 WP_010368419.1 methylisocitrate lyase -
C7V42_RS06015 1284006..1284602 + 597 WP_010368420.1 DUF1003 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9719.15 Da        Isoelectric Point: 8.0471

>T100664 WP_010368415.1 NZ_CP028127:c1280314-1280063 [Xanthomonas vasicola pv. vasculorum]
VILQFSDNAWEDSLYWQQADKKILKRISELINAIQCDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAAEGILLIAQV
RYH

Download         Length: 252 bp

>T100664 NZ_CP028127:c1280314-1280063 [Xanthomonas vasicola pv. vasculorum]
GTGATCCTCCAGTTCTCGGATAATGCCTGGGAGGACTCTCTGTACTGGCAGCAGGCCGACAAGAAGATCCTCAAACGCAT
CAGCGAATTGATCAACGCCATTCAGTGCGATCCGTTCCAAGGCATCGGCAAACCCGAGCCACTGCGCCACGCGCTAGCGG
GTTATTGGTCGCGCCGCATCAATGACGAACACCGAATCGTCTACAAAGCCGCAGAAGGAATACTACTGATCGCCCAGGTG
CGTTATCACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9224.66 Da        Isoelectric Point: 9.5902

>AT100664 WP_010368416.1 NZ_CP028127:c1280562-1280311 [Xanthomonas vasicola pv. vasculorum]
MNIITYSAARASLAETMDRVVNDHEPVIITRSGKRAVVMMSLDDYKAMKETAYLLRSPKSAQRLLESIAQLEAGRGKERG
LAE

Download         Length: 252 bp

>AT100664 NZ_CP028127:c1280562-1280311 [Xanthomonas vasicola pv. vasculorum]
ATGAATATCATCACCTACAGCGCCGCGCGCGCCTCTCTCGCAGAGACCATGGACCGCGTTGTCAACGACCACGAGCCAGT
GATCATCACGCGCAGCGGCAAACGAGCTGTCGTCATGATGTCCCTGGATGACTACAAGGCCATGAAGGAAACCGCCTACC
TGCTGCGCAGCCCGAAGAGTGCACAGCGCCTGCTGGAATCCATCGCCCAGCTTGAAGCCGGCCGCGGCAAGGAACGGGGA
CTGGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7C7F2G6

Antitoxin

Source ID Structure
AlphaFold DB A0A836ZTX6

References