Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2600931..2601165 | Replicon | chromosome |
| Accession | NZ_CP028126 | ||
| Organism | Escherichia coli O26 str. RM10386 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2600932..2601035 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2600931..2601165 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I3U_RS15840 | 2598130..2598939 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| I3U_RS15845 | 2598996..2599190 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| I3U_RS15850 | 2599183..2599371 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2599189..2599367 | - | 179 | NuclAT_1 | - | - |
| - | 2599189..2599367 | - | 179 | NuclAT_1 | - | - |
| - | 2599189..2599367 | - | 179 | NuclAT_1 | - | - |
| - | 2599189..2599367 | - | 179 | NuclAT_1 | - | - |
| I3U_RS15855 | 2599478..2599759 | + | 282 | WP_001443927.1 | excisionase | - |
| I3U_RS15860 | 2599725..2600840 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2600931..2601165 | + | 235 | - | - | Antitoxin |
| - | 2600932..2601035 | - | 104 | - | - | Toxin |
| I3U_RS15865 | 2601193..2601534 | - | 342 | WP_000976492.1 | YebY family protein | - |
| I3U_RS15870 | 2601547..2602419 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| I3U_RS15875 | 2602423..2602797 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| I3U_RS15880 | 2602936..2603166 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I3U_RS15885 | 2603268..2603924 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| I3U_RS15890 | 2603948..2604610 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2535694..2606667 | 70973 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T100643 NZ_CP028126:c2601035-2600932 [Escherichia coli O26 str. RM10386]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT100643 NZ_CP028126:2600931-2601165 [Escherichia coli O26 str. RM10386]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
