Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2255176..2255447 Replicon chromosome
Accession NZ_CP028117
Organism Escherichia coli O111 str. RM9322

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2255214..2255317 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2255176..2255447 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I3O_RS12130 2252333..2253772 + 1440 WP_000057021.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I3O_RS12135 2253890..2254126 + 237 WP_001295499.1 DUF1480 family protein -
I3O_RS12140 2254231..2254422 + 192 WP_001296140.1 YebW family protein -
I3O_RS12145 2254423..2255079 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2255176..2255447 + 272 - - Antitoxin
- 2255214..2255317 - 104 - - Toxin
I3O_RS12150 2255475..2255816 - 342 WP_000976492.1 YebY family protein -
I3O_RS12155 2255829..2256701 - 873 WP_000879274.1 copper homeostasis membrane protein CopD -
I3O_RS12160 2256705..2257079 - 375 WP_000204699.1 CopC domain-containing protein YobA -
I3O_RS12165 2257218..2257448 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I3O_RS12170 2257550..2258206 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
I3O_RS12175 2258230..2258892 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T100568 NZ_CP028117:c2255317-2255214 [Escherichia coli O111 str. RM9322]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT100568 NZ_CP028117:2255176-2255447 [Escherichia coli O111 str. RM9322]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References