Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2586921..2587155 | Replicon | chromosome |
| Accession | NZ_CP028116 | ||
| Organism | Escherichia coli O26 str. RM8426 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2586922..2587025 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2586921..2587155 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I3M_RS15170 | 2584120..2584929 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| I3M_RS15175 | 2584986..2585180 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| I3M_RS15180 | 2585173..2585361 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2585179..2585357 | - | 179 | NuclAT_1 | - | - |
| - | 2585179..2585357 | - | 179 | NuclAT_1 | - | - |
| - | 2585179..2585357 | - | 179 | NuclAT_1 | - | - |
| - | 2585179..2585357 | - | 179 | NuclAT_1 | - | - |
| I3M_RS15185 | 2585468..2585749 | + | 282 | WP_001443927.1 | excisionase | - |
| I3M_RS15190 | 2585715..2586830 | + | 1116 | WP_001189089.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2586921..2587155 | + | 235 | - | - | Antitoxin |
| - | 2586922..2587025 | - | 104 | - | - | Toxin |
| I3M_RS15195 | 2587183..2587524 | - | 342 | WP_000976492.1 | YebY family protein | - |
| I3M_RS15200 | 2587537..2588406 | - | 870 | WP_032341845.1 | copper homeostasis membrane protein CopD | - |
| I3M_RS15205 | 2588410..2588784 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| I3M_RS15210 | 2588923..2589153 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I3M_RS15215 | 2589255..2589911 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| I3M_RS15220 | 2589935..2590597 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2531964..2592654 | 60690 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T100536 NZ_CP028116:c2587025-2586922 [Escherichia coli O26 str. RM8426]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT100536 NZ_CP028116:2586921-2587155 [Escherichia coli O26 str. RM8426]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
