Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2086667..2087052 Replicon chromosome
Accession NZ_CP028094
Organism Synechocystis sp. IPPAS B-1465

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C7I86_RS09935 Protein ID WP_080504056.1
Coordinates 2086948..2087052 (+) Length 35 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C7I86_RS09930 Protein ID WP_010873096.1
Coordinates 2086667..2086951 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7I86_RS09895 2081726..2083561 + 1836 WP_010873091.1 hypothetical protein -
C7I86_RS09900 2083705..2084757 - 1053 WP_010873092.1 2OG-Fe(II) oxygenase -
C7I86_RS09905 2084984..2085211 + 228 WP_020862282.1 DUF2281 domain-containing protein -
C7I86_RS09910 2085257..2085601 + 345 WP_071822655.1 type II toxin-antitoxin system VapC family toxin -
C7I86_RS09915 2085763..2086047 + 285 WP_014407120.1 BrnT family toxin -
C7I86_RS09920 2086052..2086258 + 207 WP_010873094.1 hypothetical protein -
C7I86_RS09925 2086286..2086525 + 240 WP_010873095.1 hypothetical protein -
C7I86_RS09930 2086667..2086951 + 285 WP_010873096.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C7I86_RS09935 2086948..2087052 + 105 WP_080504056.1 type II toxin-antitoxin system YoeB family toxin Toxin
C7I86_RS09940 2087146..2087970 - 825 WP_010873097.1 photosystem II manganese-stabilizing polypeptide -
C7I86_RS09945 2088197..2088574 + 378 WP_010873098.1 hypothetical protein -
C7I86_RS09955 2088971..2089333 - 363 WP_010873099.1 hypothetical protein -
C7I86_RS09960 2089521..2090864 + 1344 WP_010873100.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-32)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(19-83)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 4196.90 Da        Isoelectric Point: 8.5633

>T100440 WP_080504056.1 NZ_CP028094:2086948-2087052 [Synechocystis sp. IPPAS B-1465]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Download         Length: 105 bp

>T100440 NZ_CP028094:2086948-2087052 [Synechocystis sp. IPPAS B-1465]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.02 Da        Isoelectric Point: 4.1364

>AT100440 WP_010873096.1 NZ_CP028094:2086667-2086951 [Synechocystis sp. IPPAS B-1465]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Download         Length: 285 bp

>AT100440 NZ_CP028094:2086667-2086951 [Synechocystis sp. IPPAS B-1465]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References