Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1934309..1934901 Replicon chromosome
Accession NZ_CP028094
Organism Synechocystis sp. IPPAS B-1465

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C7I86_RS09195 Protein ID WP_010872957.1
Coordinates 1934309..1934695 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C7I86_RS09200 Protein ID WP_010872958.1
Coordinates 1934695..1934901 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7I86_RS09185 1931980..1933152 + 1173 WP_010872955.1 sulfate adenylyltransferase -
C7I86_RS09190 1933195..1934259 + 1065 WP_010872956.1 glycosyltransferase -
C7I86_RS09195 1934309..1934695 - 387 WP_010872957.1 type II toxin-antitoxin system VapC family toxin Toxin
C7I86_RS09200 1934695..1934901 - 207 WP_010872958.1 DUF2281 domain-containing protein Antitoxin
C7I86_RS09205 1935148..1936371 - 1224 WP_010872959.1 geranylgeranyl reductase -
C7I86_RS09210 1936753..1937910 + 1158 WP_010872960.1 oxidoreductase -
C7I86_RS09215 1937927..1938238 + 312 WP_010872961.1 DUF433 domain-containing protein -
C7I86_RS09220 1938315..1939151 + 837 WP_010872962.1 DUF1049 domain-containing protein -
C7I86_RS09225 1939270..1939623 + 354 WP_010872963.1 TMEM165/GDT1 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(7-67)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14814.14 Da        Isoelectric Point: 6.0713

>T100439 WP_010872957.1 NZ_CP028094:c1934695-1934309 [Synechocystis sp. IPPAS B-1465]
MNSVLIDTHVFIWLAEDDSNLPVTTKDTLENMDNVFVSIASFWEISIKLKIGKLSLCGDFNSIEASFQRTRFKLLPITLK
DTIKLYNLPLHHKDPFDRILVSQSINHSLILVSRDQALDDYPIQRLWL

Download         Length: 387 bp

>T100439 NZ_CP028094:c1934695-1934309 [Synechocystis sp. IPPAS B-1465]
ATGAATTCTGTTTTGATAGACACCCACGTTTTTATTTGGTTAGCAGAAGATGACTCTAACTTGCCTGTGACGACAAAAGA
TACCTTAGAAAATATGGATAACGTTTTTGTTAGTATTGCCAGCTTTTGGGAAATTTCTATTAAACTAAAAATTGGTAAAC
TTTCTCTCTGTGGTGATTTCAATAGTATTGAAGCTAGTTTTCAAAGAACCCGATTCAAGCTATTACCTATTACACTAAAA
GACACAATTAAACTTTATAATCTTCCCTTGCACCACAAAGATCCCTTTGATCGTATTTTGGTATCCCAATCGATTAATCA
TTCTCTTATTTTAGTCAGTCGTGATCAAGCTCTGGATGATTATCCGATTCAACGCCTGTGGTTGTAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7699.84 Da        Isoelectric Point: 3.8804

>AT100439 WP_010872958.1 NZ_CP028094:c1934901-1934695 [Synechocystis sp. IPPAS B-1465]
MTTEAALLNIAENLPDDLKIELLHYAEYLMNKSLNAPQKPLAGSMKGTFILPLPEDFDAPLEEFEEYM

Download         Length: 207 bp

>AT100439 NZ_CP028094:c1934901-1934695 [Synechocystis sp. IPPAS B-1465]
ATGACTACTGAAGCTGCCCTATTAAACATTGCTGAAAATCTGCCTGATGACTTAAAAATCGAGCTTTTACACTATGCTGA
ATATTTAATGAATAAATCCTTAAATGCGCCCCAAAAGCCATTAGCAGGATCGATGAAAGGAACTTTTATTTTACCTCTAC
CCGAAGACTTTGATGCCCCCTTAGAAGAATTTGAGGAGTATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References