Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2080873..2081018 Replicon chromosome
Accession NZ_CP027863
Organism Klebsiella pneumoniae subsp. pneumoniae strain CRKP18622

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2080909..2081011 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2080873..2081018 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7K64_RS10065 2076003..2078063 + 2061 WP_004151449.1 oligopeptidase B -
C7K64_RS10070 2078067..2078726 - 660 WP_002911407.1 exodeoxyribonuclease X -
C7K64_RS10075 2078805..2079035 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C7K64_RS10080 2079148..2079522 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C7K64_RS10085 2079526..2080395 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
C7K64_RS10090 2080412..2080750 + 339 WP_002911404.1 YebY family protein -
- 2080873..2081018 - 146 - - Antitoxin
- 2080909..2081011 + 103 - - Toxin
C7K64_RS10095 2081386..2081529 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C7K64_RS10100 2081634..2082602 - 969 WP_014907334.1 VirK/YbjX family protein -
C7K64_RS10105 2082759..2083412 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
C7K64_RS10110 2083409..2083600 - 192 WP_002911395.1 YebW family protein -
C7K64_RS10115 2083698..2083937 - 240 WP_002911393.1 YebV family protein -
C7K64_RS10120 2084053..2085486 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T100393 NZ_CP027863:2080909-2081011 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT100393 NZ_CP027863:c2081018-2080873 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References