Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 12088..12626 Replicon chromosome
Accession NZ_CP027860
Organism Ahniella affigens strain D13

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C7S18_RS00075 Protein ID WP_106889616.1
Coordinates 12088..12390 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag C7S18_RS00080 Protein ID WP_106889617.1
Coordinates 12387..12626 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7S18_RS00040 7395..7787 + 393 WP_106889610.1 TIR domain-containing protein -
C7S18_RS00045 7797..8771 + 975 WP_106889611.1 caspase family protein -
C7S18_RS00050 8881..9117 + 237 WP_106889612.1 hypothetical protein -
C7S18_RS00055 9844..10074 + 231 WP_106889613.1 hypothetical protein -
C7S18_RS00065 10957..11412 + 456 WP_206207949.1 type II toxin-antitoxin system RelE/ParE family toxin -
C7S18_RS00070 11399..11686 + 288 WP_106889615.1 helix-turn-helix domain-containing protein -
C7S18_RS00075 12088..12390 - 303 WP_106889616.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C7S18_RS00080 12387..12626 - 240 WP_106889617.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
C7S18_RS00085 12709..13146 - 438 WP_106889618.1 hypothetical protein -
C7S18_RS00090 13366..14370 - 1005 WP_106889619.1 IS5 family transposase -
C7S18_RS00095 15004..15726 + 723 WP_106893859.1 rRNA pseudouridine synthase -
C7S18_RS00100 16140..16553 + 414 WP_106889620.1 hypothetical protein -
C7S18_RS00105 16912..17514 + 603 WP_146151684.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-71)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11333.21 Da        Isoelectric Point: 8.9269

>T100384 WP_106889616.1 NZ_CP027860:c12390-12088 [Ahniella affigens]
MRPFTLTRLAKADLRAIAVYTEEQWGVEQRNLYIRQFDDTFHLLAATPGLGKACNDIMPGYRKFPQGSHLVFYKNGIASV
IEIVRILHKSMDVEPLLIGG

Download         Length: 303 bp

>T100384 NZ_CP027860:c12390-12088 [Ahniella affigens]
ATGAGGCCCTTTACCCTCACCCGGCTCGCAAAAGCAGATCTGCGAGCCATAGCCGTCTACACCGAAGAGCAATGGGGAGT
TGAGCAGAGAAACCTGTACATCAGGCAGTTTGATGACACCTTCCACCTGCTCGCGGCCACGCCTGGGCTCGGGAAGGCCT
GCAACGACATCATGCCAGGCTACCGCAAGTTCCCTCAGGGAAGCCACTTGGTCTTCTACAAGAACGGCATTGCCAGCGTC
ATTGAGATCGTCCGCATCCTGCACAAGAGCATGGACGTAGAGCCGTTGCTGATTGGCGGATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8795.84 Da        Isoelectric Point: 5.1069

>AT100384 WP_106889617.1 NZ_CP027860:c12626-12387 [Ahniella affigens]
MAKNTSVSLGEHFEGFIAQQIENGRYGSASEVVRAGLRLLEDAENKLGALRRMLAEGEQSGIANYNYNEFMAELDTRKK

Download         Length: 240 bp

>AT100384 NZ_CP027860:c12626-12387 [Ahniella affigens]
ATGGCGAAGAACACCAGCGTCAGCCTGGGCGAGCACTTCGAGGGCTTCATTGCTCAACAGATCGAAAACGGCCGCTACGG
CTCTGCCAGCGAGGTAGTACGGGCCGGTCTGCGCCTGCTTGAGGACGCCGAAAACAAGCTAGGAGCCCTGCGCCGCATGC
TGGCCGAAGGCGAGCAAAGCGGTATCGCCAACTACAACTACAACGAGTTCATGGCCGAGCTAGATACCCGCAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References