Detailed information of TA system TA100365

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 1165303..1165808
• Replicon: chromosome
• Accession: NZ_CP027845
• Organism: Candidatus Phycorickettsia trachydisci isolate CCALA 838

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: phytr_RS05040
• Protein ID: WP_106874783.1
• Coordinates: 1165303..1165557 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: phytr_RS05045
• Protein ID: WP_106874784.1
• Coordinates: 1165557..1165808 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
phytr_RS05030	1160644..1161999	+	1356	WP_158706876.1	ankyrin repeat domain-containing protein	-
phytr_RS05035	1162085..1165246	-	3162	WP_106874782.1	tetratricopeptide repeat protein	-
phytr_RS05040	1165303..1165557	-	255	WP_106874783.1	Txe/YoeB family addiction module toxin	Toxin
phytr_RS05045	1165557..1165808	-	252	WP_106874784.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
phytr_RS05050	1165916..1166347	-	432	WP_106874785.1	helix-turn-helix domain-containing protein	-
phytr_RS05055	1167420..1168367	-	948	WP_106874786.1	Rpn family recombination-promoting nuclease/putative transposase	-
phytr_RS05060	1168423..1169805	-	1383	WP_106874787.1	tetratricopeptide repeat protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10222.86 Da
• Isoelectric Point: 9.6426

>T100365 WP_106874783.1 NZ_CP027845:c1165557-1165303 [Candidatus Phycorickettsia trachydisci]
MDILFHKNAWEDYVYFLEHDKKIIVKINQIIKDITRNPFHGIGKPEALKHTLSGLWSRRINHEHRLVYTVKDSTIYILQC
RYHY

Nucleotide

• Length: 255 bp

>T100365 NZ_CP027845:c1165557-1165303 [Candidatus Phycorickettsia trachydisci]
ATGGATATATTATTTCATAAAAACGCTTGGGAGGATTATGTCTATTTTTTAGAACATGATAAAAAAATTATAGTTAAAAT
TAATCAGATTATTAAAGATATAACACGAAATCCTTTTCATGGTATAGGCAAGCCTGAAGCCTTGAAGCATACTTTATCGG
GATTATGGTCAAGAAGAATAAATCATGAGCATAGATTAGTATATACCGTTAAAGATTCTACTATTTATATCTTACAATGT
AGATATCACTATTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9570.99 Da
• Isoelectric Point: 5.6981

>AT100365 WP_106874784.1 NZ_CP027845:c1165808-1165557 [Candidatus Phycorickettsia trachydisci]
MEAISYTKARKSLATLMDEVCENHDQVIITRQKQKSVVIMSLDDYNALEETAYLLKGIKNAQRLSKAMDDLKEDKNFIPQ
HIE

Nucleotide

• Length: 252 bp

>AT100365 NZ_CP027845:c1165808-1165557 [Candidatus Phycorickettsia trachydisci]
ATGGAAGCTATATCTTACACAAAAGCTCGTAAGAGCTTAGCGACTCTCATGGATGAGGTTTGTGAAAATCATGATCAAGT
TATTATTACTAGACAAAAACAGAAATCAGTAGTGATAATGTCTTTGGATGATTACAATGCTTTAGAAGAAACTGCCTATT
TACTTAAAGGCATAAAAAATGCTCAAAGGTTAAGCAAAGCAATGGATGATTTGAAAGAAGATAAAAATTTTATACCCCAG
CATATTGAATAA