Detailed information of TA system TA100361

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 178633..179107
• Replicon: chromosome
• Accession: NZ_CP027806
• Organism: Candidatus Cyclonatronum proteinivorum strain Omega

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: CYPRO_RS00620
• Protein ID: WP_114982655.1
• Coordinates: 178633..178905 (-)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: CYPRO_RS00625
• Protein ID: WP_114982656.1
• Coordinates: 178889..179107 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CYPRO_RS00610	175408..176799	+	1392	WP_114982653.1	protoporphyrinogen oxidase	-
CYPRO_RS00615	177046..178401	-	1356	WP_114982654.1	metallophosphoesterase	-
CYPRO_RS00620	178633..178905	-	273	WP_114982655.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CYPRO_RS00625	178889..179107	-	219	WP_114982656.1	ribbon-helix-helix protein, CopG family	Antitoxin
CYPRO_RS00630	179470..180618	-	1149	WP_114982657.1	methionine adenosyltransferase	-
CYPRO_RS00640	181211..182134	-	924	WP_114982659.1	T9SS type A sorting domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-87)

Antitoxin

• Protein of unknown function DUF6290 (1-64)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 11007.79 Da
• Isoelectric Point: 10.8372

>T100361 WP_114982655.1 NZ_CP027806:c178905-178633 [Candidatus Cyclonatronum proteinivorum]
MTWRVEFDNRARKELRKLDVATQDRILKWMRDNLSTDNDPQRMGSSLKGRMKGLWRYRVNDYRIICQIQDDKVLILVVRI
GHRRDIYDKK

Nucleotide

• Length: 273 bp

>T100361 NZ_CP027806:c178905-178633 [Candidatus Cyclonatronum proteinivorum]
ATGACCTGGAGGGTTGAGTTTGATAACCGCGCTCGAAAAGAGCTCCGGAAATTAGACGTTGCAACACAGGATAGAATTCT
GAAATGGATGCGTGATAATTTGTCAACTGACAACGATCCACAAAGAATGGGGAGTTCTCTTAAAGGGCGGATGAAAGGGT
TATGGCGCTACCGGGTCAATGATTATCGGATTATCTGCCAAATTCAGGATGATAAAGTGCTCATTTTGGTTGTTCGGATT
GGGCATAGAAGAGATATTTACGATAAGAAGTAG

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 8540.70 Da
• Isoelectric Point: 7.0165

>AT100361 WP_114982656.1 NZ_CP027806:c179107-178889 [Candidatus Cyclonatronum proteinivorum]
MSITIRLDSVLKKRLHKLAKQTGRTKSSFVRQALEEKLDDLEDLYVAERRLEQPESKNWSLEQLERRDDLEG

Nucleotide

• Length: 219 bp

>AT100361 NZ_CP027806:c179107-178889 [Candidatus Cyclonatronum proteinivorum]
ATGTCAATCACAATCAGACTGGACTCAGTTTTAAAAAAGCGGCTTCATAAACTTGCCAAACAGACCGGTCGTACCAAATC
ATCTTTTGTCCGTCAGGCGCTGGAAGAAAAATTGGATGATCTGGAAGATTTGTATGTAGCTGAACGTCGCCTTGAGCAAC
CCGAAAGCAAAAACTGGAGTTTGGAACAATTAGAGCGGAGAGATGACCTGGAGGGTTGA