Detailed information of TA system TA100304

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2511697..2512190
• Replicon: chromosome
• Accession: NZ_CP027786
• Organism: Tetragenococcus koreensis strain KCTC 3924

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C7K43_RS11980
• Protein ID: WP_124007044.1
• Coordinates: 2511924..2512190 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C7K43_RS11975
• Protein ID: WP_124007043.1
• Coordinates: 2511697..2511927 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7K43_RS11955	2506852..2507313	+	462	WP_124007039.1	PTS sugar transporter subunit IIA	-
C7K43_RS11960	2507310..2507633	+	324	WP_124007040.1	fructose PTS transporter subunit IIB	-
C7K43_RS11965	2507653..2508756	+	1104	WP_124007041.1	PTS fructose transporter subunit IIC	-
C7K43_RS11970	2508795..2511476	+	2682	WP_124007042.1	mannosylglycerate hydrolase	-
C7K43_RS11975	2511697..2511927	+	231	WP_124007043.1	antitoxin	Antitoxin
C7K43_RS11980	2511924..2512190	+	267	WP_124007044.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C7K43_RS11985	2512378..2512560	-	183	WP_124007045.1	putative holin-like toxin	-
C7K43_RS11990	2512748..2513395	-	648	WP_124007046.1	pyroglutamyl-peptidase I	-
C7K43_RS11995	2513722..2514642	-	921	WP_124007047.1	DUF979 domain-containing protein	-
C7K43_RS12000	2514626..2515333	-	708	WP_124007048.1	DUF969 domain-containing protein	-
C7K43_RS12005	2515643..2515888	+	246	WP_124007049.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
C7K43_RS12010	2515878..2516162	+	285	WP_124007050.1	type II toxin-antitoxin system YafQ family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-87)

Antitoxin

• Protein of unknown function DUF6290 (1-71)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10578.25 Da
• Isoelectric Point: 10.5428

>T100304 WP_124007044.1 NZ_CP027786:2511924-2512190 [Tetragenococcus koreensis]
MSYRLIFSSEIQKQFRKMDKYQATLITRWLYQHIDGIDNPRKFGKVLTANRSGQWRYRIGKYRVIVEIEDSQLVVLAVQV
GHRKNIYD

Nucleotide

• Length: 267 bp

>T100304 NZ_CP027786:2511924-2512190 [Tetragenococcus koreensis]
ATGAGCTATCGCTTAATCTTTTCTTCTGAAATACAAAAACAGTTTAGAAAAATGGATAAATATCAAGCTACTTTAATTAC
TCGTTGGCTATATCAGCATATTGACGGAATTGACAATCCTCGCAAATTTGGAAAAGTGCTAACTGCAAACCGGTCTGGTC
AATGGCGCTATAGAATTGGCAAATATCGCGTTATTGTTGAAATAGAAGACAGCCAATTAGTTGTACTAGCTGTTCAAGTT
GGGCATAGGAAAAATATTTACGATTAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8899.96 Da
• Isoelectric Point: 3.9370

>AT100304 WP_124007043.1 NZ_CP027786:2511697-2511927 [Tetragenococcus koreensis]
MAMITVRVSDSEKEWLNYMADFYGISLSDLLKTYSMEQLEDEYDRQTADIAYKRWLENGKQTVSMDEILSEFGGLE

Nucleotide

• Length: 231 bp

>AT100304 NZ_CP027786:2511697-2511927 [Tetragenococcus koreensis]
ATGGCTATGATCACAGTACGTGTAAGTGACTCAGAAAAAGAATGGTTGAATTATATGGCCGATTTCTATGGGATCTCTTT
GTCTGATCTTTTAAAAACATATTCGATGGAACAATTAGAAGACGAGTATGACCGTCAAACGGCTGATATTGCGTATAAAC
GTTGGCTAGAAAATGGTAAACAAACAGTATCAATGGATGAAATCCTTTCTGAATTTGGAGGTTTGGAATGA