Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 695654..696195 Replicon chromosome
Accession NZ_CP027786
Organism Tetragenococcus koreensis strain KCTC 3924

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C7K43_RS03310 Protein ID WP_124005553.1
Coordinates 695968..696195 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C7K43_RS03305 Protein ID WP_124005552.1
Coordinates 695654..695929 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7K43_RS03275 690822..691715 - 894 WP_124005546.1 tyrosine-type recombinase/integrase -
C7K43_RS03280 691712..691921 - 210 WP_157977726.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
C7K43_RS03285 692195..693643 + 1449 WP_124005548.1 DDE-type integrase/transposase/recombinase -
C7K43_RS03290 693920..694429 - 510 WP_124005549.1 QueT transporter family protein -
C7K43_RS03295 694552..695292 - 741 WP_124005550.1 3-oxoacyl-ACP reductase -
C7K43_RS03300 695289..695513 - 225 WP_124005551.1 DUF2829 domain-containing protein -
C7K43_RS03305 695654..695929 + 276 WP_124005552.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C7K43_RS03310 695968..696195 + 228 WP_124005553.1 type II toxin-antitoxin system YafQ family toxin Toxin
C7K43_RS03315 696290..696757 - 468 WP_124005554.1 YbaK/EbsC family protein -
C7K43_RS03320 696999..697961 - 963 WP_124005555.1 D-2-hydroxyacid dehydrogenase -
C7K43_RS03325 698254..699500 - 1247 Protein_643 catalase -
C7K43_RS03330 699857..700348 - 492 WP_124005556.1 MepB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-75)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(10-87)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 9236.65 Da        Isoelectric Point: 7.5219

>T100303 WP_124005553.1 NZ_CP027786:695968-696195 [Tetragenococcus koreensis]
MKKHYNPEKFEQVLELLVHRHQSELIRIYKDHSLTGNWQGFRELHIEKDWLLIYKIDNNKLILTLTRTDKHDELL

Download         Length: 228 bp

>T100303 NZ_CP027786:695968-696195 [Tetragenococcus koreensis]
ATGAAAAAACATTATAATCCAGAAAAATTTGAGCAGGTTCTAGAACTGCTAGTTCACAGACACCAAAGTGAACTAATCAG
AATTTACAAAGATCACTCGTTGACAGGAAATTGGCAAGGTTTCCGTGAATTGCATATTGAAAAAGATTGGCTACTTATTT
ATAAGATTGACAATAATAAGCTTATCCTTACTCTCACTCGCACCGACAAACATGACGAATTATTATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10400.47 Da        Isoelectric Point: 4.1754

>AT100303 WP_124005552.1 NZ_CP027786:695654-695929 [Tetragenococcus koreensis]
MSDKNRNDTRLSIRIDGELKEQAKEVYSELGMDLTTAVTIFLKQSVRESSIPFQPHLENPDNIQARQEANSDNLETFDTV
KELMESLNAED

Download         Length: 276 bp

>AT100303 NZ_CP027786:695654-695929 [Tetragenococcus koreensis]
ATGAGCGATAAAAACCGTAATGATACCCGTTTAAGCATTCGTATTGACGGTGAACTAAAAGAACAAGCTAAAGAAGTTTA
CAGTGAACTAGGTATGGACTTAACAACTGCTGTCACCATTTTTCTTAAACAATCTGTAAGAGAAAGTAGTATACCTTTCC
AACCTCATTTAGAAAATCCAGATAATATTCAAGCGAGGCAGGAAGCAAATTCAGATAATCTTGAAACTTTCGATACAGTA
AAAGAACTTATGGAGAGTTTAAATGCTGAAGACTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References