100302

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1980382..1980939 Replicon chromosome
Accession NZ_CP027783
Organism Tetragenococcus osmophilus strain JCM 31126

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C7K38_RS09605 Protein ID WP_123936385.1
Coordinates 1980382..1980651 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C7K38_RS09610 Protein ID WP_123936386.1
Coordinates 1980655..1980939 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7K38_RS09585 1976263..1977111 + 849 WP_123936382.1 DegV family protein -
C7K38_RS09590 1977205..1978470 - 1266 WP_123936713.1 cytochrome P450 -
C7K38_RS09595 1978611..1979627 + 1017 WP_123936383.1 hypothetical protein -
C7K38_RS09600 1979688..1980158 + 471 WP_123936384.1 GNAT family N-acetyltransferase -
C7K38_RS09605 1980382..1980651 - 270 WP_123936385.1 type II toxin-antitoxin system YafQ family toxin Toxin
C7K38_RS09610 1980655..1980939 - 285 WP_123936386.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C7K38_RS09615 1981154..1981519 - 366 WP_123936387.1 energy-coupled thiamine transporter ThiT -
C7K38_RS09620 1981565..1981720 - 156 WP_123936388.1 energy-coupled thiamine transporter ThiT -
C7K38_RS09630 1982291..1982758 - 468 WP_123936389.1 YbaK/EbsC family protein -
C7K38_RS09635 1982837..1983136 - 300 WP_123936390.1 hypothetical protein -
C7K38_RS09640 1983375..1984337 - 963 WP_123936391.1 D-2-hydroxyacid dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-92)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10813.43 Da        Isoelectric Point: 9.0310

>T100302 WP_123936385.1 NZ_CP027783:c1980651-1980382 [Tetragenococcus osmophilus]
MYKVVTSSRFKKDYKLCQKRRLPIEQLDQVIVRLARGENLEEKFKNHTLTGKYKGYEECHIQPDCLFVYEYRKDELFLYR
TGTHSDLFN

Download         Length: 270 bp

>T100302 NZ_CP027783:c1980651-1980382 [Tetragenococcus osmophilus]
ATGTATAAAGTTGTTACGTCTTCTCGTTTTAAAAAGGATTATAAATTGTGTCAAAAAAGAAGGTTACCCATTGAACAGTT
GGATCAAGTAATTGTACGTTTAGCGAGAGGCGAAAACTTAGAGGAGAAGTTTAAGAATCATACTTTGACTGGTAAATACA
AAGGATATGAAGAATGTCATATTCAGCCTGATTGCTTGTTTGTTTATGAGTATAGAAAAGATGAATTGTTTTTATACCGT
ACAGGGACACATTCAGATTTATTTAATTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11097.50 Da        Isoelectric Point: 4.4393

>AT100302 WP_123936386.1 NZ_CP027783:c1980939-1980655 [Tetragenococcus osmophilus]
MSKSLKEKNENKVVQARINKELVDEAEDIFNDLGIDRSTAMRIFYQQVVWNNGLPFEMKRPEVPNEETVKAFEEDLTNAK
RYTDLDELFKDLKE

Download         Length: 285 bp

>AT100302 NZ_CP027783:c1980939-1980655 [Tetragenococcus osmophilus]
ATGAGTAAAAGTCTAAAAGAAAAAAATGAAAATAAAGTTGTCCAAGCTCGCATAAATAAAGAGTTGGTTGATGAAGCAGA
AGATATTTTTAATGATTTAGGTATTGATCGTTCGACTGCAATGAGAATTTTTTATCAACAAGTTGTTTGGAATAATGGTC
TGCCTTTTGAAATGAAACGTCCTGAGGTTCCTAATGAAGAGACTGTTAAGGCGTTTGAAGAAGATTTAACTAATGCAAAG
AGGTATACTGATTTAGATGAATTATTTAAAGATTTGAAGGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References