Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 2277853..2278622 Replicon chromosome
Accession NZ_CP027770
Organism Staphylococcus felis strain ATCC 49168

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag C7J90_RS12015 Protein ID WP_167389000.1
Coordinates 2277853..2278005 (-) Length 51 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag C7J90_RS10690 Protein ID WP_103208491.1
Coordinates 2278023..2278622 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7J90_RS10675 2274246..2275772 - 1527 WP_103208497.1 exopolyphosphatase -
C7J90_RS10680 2275794..2277179 - 1386 WP_103208495.1 class II fumarate hydratase -
C7J90_RS10685 2277342..2277740 - 399 WP_103208493.1 hypothetical protein -
C7J90_RS12015 2277853..2278005 - 153 WP_167389000.1 hypothetical protein Toxin
C7J90_RS10690 2278023..2278622 - 600 WP_103208491.1 glucosamine-6-phosphate isomerase Antitoxin
C7J90_RS10695 2278746..2279216 - 471 WP_103208489.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
C7J90_RS10700 2279219..2280346 - 1128 WP_103208487.1 tRNA epoxyqueuosine(34) reductase QueG -
C7J90_RS10705 2280648..2281370 - 723 WP_103208485.1 amino acid ABC transporter ATP-binding protein -
C7J90_RS10710 2281363..2282817 - 1455 WP_103208483.1 ABC transporter substrate-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(124-197)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5983.40 Da        Isoelectric Point: 3.9129

>T100296 WP_167389000.1 NZ_CP027770:c2278005-2277853 [Staphylococcus felis]
MYQDKKDYDNEMVDGFDDMVELGKEMEQISEENDQEKLNQDHNQAVRSDK

Download         Length: 153 bp

>T100296 NZ_CP027770:c2278005-2277853 [Staphylococcus felis]
ATGTATCAAGACAAAAAAGATTATGATAATGAAATGGTCGATGGTTTTGACGATATGGTAGAACTTGGTAAGGAGATGGA
ACAAATTTCTGAAGAAAATGACCAAGAAAAGCTCAATCAAGACCATAATCAAGCAGTGCGTTCTGATAAATGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22340.43 Da        Isoelectric Point: 5.8847

>AT100296 WP_103208491.1 NZ_CP027770:c2278622-2278023 [Staphylococcus felis]
MAMNFKIFKDADTAALYTADIIRKQFNNNPTTIAGIHLNNEDAPVLEALKKSVDDHAVDFSQIHILDYDKKTSYYKALGV
PEKQVHEIAEEEQVESFIEHHAKTKNNKGKLTLQVVTIDQKGYLGVGMKEGILPAREIILVITGDYKADLVKKLYEENGN
TSFIPSTLKQHRMVNVVLDEAAAQGLPEDVRSYFTSLYA

Download         Length: 600 bp

>AT100296 NZ_CP027770:c2278622-2278023 [Staphylococcus felis]
ATGGCAATGAATTTTAAAATTTTTAAAGATGCAGATACAGCAGCGCTTTATACAGCTGATATTATTAGAAAACAATTTAA
TAATAATCCGACTACAATCGCAGGTATTCACTTAAATAATGAAGATGCGCCAGTACTAGAAGCGTTGAAAAAAAGCGTTG
ATGATCATGCGGTAGATTTTAGCCAAATTCATATTTTAGATTACGATAAAAAAACATCTTACTATAAAGCTTTAGGTGTG
CCAGAAAAACAAGTGCATGAAATTGCAGAAGAAGAGCAAGTGGAGAGTTTTATCGAGCACCATGCTAAAACAAAAAATAA
TAAAGGTAAATTAACGCTTCAAGTTGTGACAATAGATCAAAAAGGTTATCTTGGTGTAGGGATGAAAGAAGGTATACTCC
CTGCTCGTGAAATTATTTTAGTTATCACTGGTGACTACAAAGCAGATTTAGTAAAAAAACTATATGAAGAAAATGGGAAT
ACAAGTTTTATCCCATCGACACTTAAACAGCATAGAATGGTCAATGTGGTTTTAGATGAAGCTGCTGCACAAGGGCTACC
TGAAGATGTCCGTTCGTATTTCACTTCATTATATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References