Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 6397..6927 Replicon chromosome
Accession NZ_CP027770
Organism Staphylococcus felis strain ATCC 49168

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag C7J90_RS00045 Protein ID WP_103207265.1
Coordinates 6397..6756 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag C7J90_RS00050 Protein ID WP_103207266.1
Coordinates 6757..6927 (-) Length 57 a.a.

Genomic Context


C7J90_RS00025C7J90_RS00030C7J90_RS00035C7J90_RS00040C7J90_RS00045C7J90_RS00050C7J90_RS00055C7J90_RS00060C7J90_RS00065C7J90_RS00070C7J90_RS00075
Location: 3515..4285 (771 bp)
Type: Others
Protein ID: WP_103207260.1
Location: 4260..4739 (480 bp)
Type: Others
Protein ID: WP_103207378.1
Location: 4742..5068 (327 bp)
Type: Others
Protein ID: WP_103207262.1
Location: 5146..6150 (1005 bp)
Type: Others
Protein ID: WP_103207263.1
Location: 6397..6756 (360 bp)
Type: Toxin
Protein ID: WP_103207265.1
Location: 6757..6927 (171 bp)
Type: Antitoxin
Protein ID: WP_103207266.1
Location: 7009..8157 (1149 bp)
Type: Others
Protein ID: WP_103207268.1
Location: 8285..8641 (357 bp)
Type: Others
Protein ID: WP_103207269.1
Location: 8638..9183 (546 bp)
Type: Others
Protein ID: WP_103207271.1
Location: 9164..10681 (1518 bp)
Type: Others
Protein ID: WP_103207272.1
Location: 10674..11147 (474 bp)
Type: Others
Protein ID: WP_103207274.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C7J90_RS000253515..4285-771WP_103207260.1RNA polymerase sigma factor SigB-
C7J90_RS000304260..4739-480WP_103207378.1anti-sigma B factor RsbW-
C7J90_RS000354742..5068-327WP_103207262.1anti-sigma factor antagonist-
C7J90_RS000405146..6150-1005WP_103207263.1PP2C family protein-serine/threonine phosphatase-
C7J90_RS000456397..6756-360WP_103207265.1type II toxin-antitoxin system PemK/MazF family toxinToxin
C7J90_RS000506757..6927-171WP_103207266.1antitoxin MazEAntitoxin
C7J90_RS000557009..8157-1149WP_103207268.1alanine racemase-
C7J90_RS000608285..8641-357WP_103207269.1holo-ACP synthase-
C7J90_RS000658638..9183-546WP_103207271.1PH domain-containing protein-
C7J90_RS000709164..10681-1518WP_103207272.1PH domain-containing protein-
C7J90_RS0007510674..11147-474WP_103207274.1PH domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-111)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 120 a.a.        Molecular weight: 13331.49 Da        Isoelectric Point: 10.1421

>T100294 WP_103207265.1 NZ_CP027770:c6756-6397 [Staphylococcus felis]
MKRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKQKYKLDKDSVILLEQIRT
VDKKRLKEKLTYLSDEKMKEVNNALGISLGLHMNQSKKD

Download         Length: 360 bp

>T100294 NZ_CP027770:c6756-6397 [Staphylococcus felis]
ATGAAGCGAGGAGACGTTTATTTAGCAGATCTCTCTCCAGTACAAGGGTCCGAACAAGGGGGAGTAAGACCCGTCGTTAT
TATTCAAAATGATACTGGAAACAAATACAGTCCAACAGTTATAGTTGCTGCTATAACAGGTAGGATTAATAAAGCTAAAA
TACCCACTCATGTTGAAATTGAAAAACAGAAATATAAGTTAGACAAAGATTCTGTTATCCTGTTAGAACAAATTAGAACA
GTAGATAAAAAGAGGCTGAAGGAGAAATTGACATATTTATCAGATGAGAAGATGAAGGAAGTCAATAATGCTCTTGGTAT
CAGCTTAGGATTGCATATGAATCAGTCTAAAAAAGACTAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6337.91 Da        Isoelectric Point: 4.0644

>AT100294 WP_103207266.1 NZ_CP027770:c6927-6757 [Staphylococcus felis]
MSTFNQTRFKNNLEQSLKEGYVQMADLNLSLATEAYSVECEACDCNESHLTNSKDD

Download         Length: 171 bp

>AT100294 NZ_CP027770:c6927-6757 [Staphylococcus felis]
ATGTCAACATTCAATCAAACAAGATTTAAAAATAATCTAGAACAGTCTTTAAAAGAAGGTTACGTACAAATGGCTGACCT
AAATCTCTCCCTAGCAACCGAAGCCTACTCAGTAGAATGTGAAGCTTGTGACTGTAACGAATCTCACTTAACGAATAGCA
AGGATGACTAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References