Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1816255..1816489 | Replicon | chromosome |
| Accession | NZ_CP027766 | ||
| Organism | Escherichia coli strain 2013C-3342 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1816256..1816359 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1816255..1816489 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C7M85_RS10185 | 1813203..1814255 | + | 1053 | Protein_1873 | recombinase RecT | - |
| C7M85_RS10190 | 1814319..1814513 | + | 195 | WP_010989194.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| C7M85_RS10195 | 1814506..1814694 | + | 189 | WP_024177035.1 | DUF1187 family protein | - |
| - | 1814512..1814690 | - | 179 | NuclAT_0 | - | - |
| - | 1814512..1814690 | - | 179 | NuclAT_0 | - | - |
| - | 1814512..1814690 | - | 179 | NuclAT_0 | - | - |
| - | 1814512..1814690 | - | 179 | NuclAT_0 | - | - |
| C7M85_RS10200 | 1814801..1815082 | + | 282 | WP_005127484.1 | excisionase | - |
| C7M85_RS10205 | 1815048..1816124 | + | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1816255..1816489 | + | 235 | - | - | Antitoxin |
| - | 1816256..1816359 | - | 104 | - | - | Toxin |
| C7M85_RS10210 | 1816517..1816858 | - | 342 | WP_000976492.1 | YebY family protein | - |
| C7M85_RS10215 | 1816871..1817743 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| C7M85_RS10220 | 1817747..1818121 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| C7M85_RS10225 | 1818260..1818490 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| C7M85_RS10230 | 1818592..1819248 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| C7M85_RS10235 | 1819272..1819934 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | espK / espN / espX7/nleL | 1737215..1821991 | 84776 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T100266 NZ_CP027766:c1816359-1816256 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT100266 NZ_CP027766:1816255-1816489 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
