100259

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4979204..4980939 Replicon chromosome
Accession NZ_CP027761
Organism Pseudomonas sp. R11-23-07

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J84_RS22775 Protein ID WP_124371996.1
Coordinates 4979204..4979848 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J84_RS22780 Protein ID WP_124371997.1
Coordinates 4979845..4980939 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J84_RS22755 4974225..4976219 - 1995 WP_124436157.1 ATP-binding protein -
C4J84_RS22760 4976581..4977684 - 1104 WP_124371994.1 DUF91 domain-containing protein -
C4J84_RS22765 4977900..4978135 - 236 Protein_4383 hypothetical protein -
C4J84_RS22770 4978635..4979207 + 573 WP_124371995.1 DUF4433 domain-containing protein -
C4J84_RS22775 4979204..4979848 + 645 WP_124371996.1 DUF4433 domain-containing protein Toxin
C4J84_RS22780 4979845..4980939 + 1095 WP_124371997.1 macro domain-containing protein Antitoxin
C4J84_RS22790 4981125..4981949 - 825 Protein_4387 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J84_RS22795 4981939..4982703 - 765 WP_124371998.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J84_RS22800 4982912..4983544 + 633 WP_057724871.1 hydrolase -
C4J84_RS22805 4983606..4984637 - 1032 WP_124371999.1 DUF1016 family protein -
C4J84_RS22815 4984831..4985007 + 177 WP_124372000.1 MerR family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24891.41 Da        Isoelectric Point: 6.4931

>T100259 WP_124371996.1 NZ_CP027761:4979204-4979848 [Pseudomonas sp. R11-23-07]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVNIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLENLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVAARGLTLPVHARPGWYFP

Download         Length: 645 bp

>T100259 NZ_CP027761:4979204-4979848 [Pseudomonas sp. R11-23-07]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTTCATCGCGACAATCTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCAGGCTGCGCAATATGTGAACATAGGCAATGTTGATTTAATCGATAAAC
GCCGCACGCGCTGTGTCCCCATTGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCATTCCGGCTGGAGCGTTCAGCAACGCAGCAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAATGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGAGAATCTCCACGAGATCGATTGGTCTATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACACCGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCGCAAGAGGCCTGACGTTGCCTGTACATGCTCGTCCGGGATGGTATTTTC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41201.24 Da        Isoelectric Point: 6.2456

>AT100259 WP_124371997.1 NZ_CP027761:4979845-4980939 [Pseudomonas sp. R11-23-07]
MIRFTQGNLLEANTEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVKTGEVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWIIEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRNG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPALREA
LKQWDGGVAAAARKNKLFDDQALDIALKRLTSSSFSHQMASCHI

Download         Length: 1095 bp

>AT100259 NZ_CP027761:4979845-4980939 [Pseudomonas sp. R11-23-07]
ATGATCAGATTCACTCAGGGTAACCTTCTGGAAGCCAACACCGAAGTCCTCGTCAACACGGTGAATACCGTGGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGCAGAAAACTATCGCTTGTACGCTGCTGCCTGTAAAGCTGGCG
AAGTAAAGACCGGAGAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAATCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCGGTGGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTGAAATGGCCGGACGTTCGCGAACAGATTGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAACGGT
GTAGAAAAGCTTACGCCTGCGCGAGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGCATGGAATGCAGCCT
GCTTGAGATTCAGAAACTGGCTTGGTTCCTGGAACGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGATCTTA
AATTTGTTGCTCATAAGTACGGGCCGTATGCCAACCGGCTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGAATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTCTACAAACCTA
TCTCAGAACAGAGGCCAAGGAATATTCCCAGGCCTTGGAGCTTACCGCGGAGTTGATTGATGGCTTTGAGTCACCCTTCG
GCATGGAGCTATTGGCAACAGTCGACTGGCTGCTGACCCAGGAAGATGTAGCCCCAACGGTTCCGGCTTTACGTGAGGCA
CTGAAACAATGGGATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACTTCCAGCAGCTTCAGCCATCAAATGGCTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References