Detailed information of TA system TA100258

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 4593253..4593758
• Replicon: chromosome
• Accession: NZ_CP027761
• Organism: Pseudomonas sp. R11-23-07

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J84_RS21055
• Protein ID: WP_124408130.1
• Coordinates: 4593504..4593758 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: C4J84_RS21050
• Protein ID: WP_124368289.1
• Coordinates: 4593253..4593507 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J84_RS21030	4588460..4588666	+	207	WP_124436031.1	hypothetical protein	-
C4J84_RS21035	4588780..4590672	+	1893	WP_124436032.1	alkaline phosphatase family protein	-
C4J84_RS21040	4590790..4591803	+	1014	WP_124436033.1	diguanylate cyclase	-
C4J84_RS21045	4591909..4593159	+	1251	WP_124371792.1	aspartate aminotransferase family protein	-
C4J84_RS21050	4593253..4593507	+	255	WP_124368289.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
C4J84_RS21055	4593504..4593758	+	255	WP_124408130.1	Txe/YoeB family addiction module toxin	Toxin
C4J84_RS21060	4593861..4594577	+	717	WP_124420791.1	hypothetical protein	-
C4J84_RS21065	4594587..4595708	-	1122	WP_124436034.1	aminotransferase class V-fold PLP-dependent enzyme	-
C4J84_RS21070	4595710..4596912	-	1203	WP_124436035.1	MFS transporter	-
C4J84_RS21075	4596912..4598162	-	1251	WP_124364335.1	ATP-grasp domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10079.60 Da
• Isoelectric Point: 7.2746

>T100258 WP_124408130.1 NZ_CP027761:4593504-4593758 [Pseudomonas sp. R11-23-07]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDEVQILMC
RYHY

Nucleotide

• Length: 255 bp

>T100258 NZ_CP027761:4593504-4593758 [Pseudomonas sp. R11-23-07]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTGTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GCTACTGGTCCCGGCGAATCACAGCAGAGCATCGTTTGGTGTATGGCATCGAGGAGGATGAAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9599.97 Da
• Isoelectric Point: 6.7262

>AT100258 WP_124368289.1 NZ_CP027761:4593253-4593507 [Pseudomonas sp. R11-23-07]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Nucleotide

• Length: 255 bp

>AT100258 NZ_CP027761:4593253-4593507 [Pseudomonas sp. R11-23-07]
ATGGAAACTATCAACTACACCCATGCGCGTGCGCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TACTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA