Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 4578935..4579977 | Replicon | chromosome |
Accession | NZ_CP027761 | ||
Organism | Pseudomonas sp. R11-23-07 |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | - |
Locus tag | C4J84_RS20970 | Protein ID | WP_124371779.1 |
Coordinates | 4578935..4579510 (-) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | - |
Locus tag | C4J84_RS20975 | Protein ID | WP_124371780.1 |
Coordinates | 4579507..4579977 (-) | Length | 157 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4J84_RS20945 | 4576349..4576684 | + | 336 | WP_124436024.1 | hypothetical protein | - |
C4J84_RS20950 | 4576774..4577124 | - | 351 | WP_124405846.1 | hypothetical protein | - |
C4J84_RS20955 | 4577336..4577665 | + | 330 | WP_124371776.1 | hypothetical protein | - |
C4J84_RS20960 | 4577673..4578308 | - | 636 | WP_124371777.1 | LysE family translocator | - |
C4J84_RS20965 | 4578445..4578816 | + | 372 | WP_124371778.1 | PH domain-containing protein | - |
C4J84_RS20970 | 4578935..4579510 | - | 576 | WP_124371779.1 | PIN domain-containing protein | Toxin |
C4J84_RS20975 | 4579507..4579977 | - | 471 | WP_124371780.1 | helix-turn-helix domain-containing protein | Antitoxin |
C4J84_RS20980 | 4580163..4580432 | + | 270 | Protein_4040 | detoxification | - |
C4J84_RS20985 | 4580485..4580772 | + | 288 | WP_124436025.1 | cloacin | - |
C4J84_RS20990 | 4580789..4581259 | + | 471 | WP_124436349.1 | hypothetical protein | - |
C4J84_RS20995 | 4581308..4581682 | - | 375 | WP_124371782.1 | cytochrome c family protein | - |
C4J84_RS21000 | 4581907..4582287 | + | 381 | WP_124364322.1 | response regulator | - |
C4J84_RS21005 | 4582481..4583095 | + | 615 | WP_124436026.1 | biliverdin-producing heme oxygenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21699.18 Da Isoelectric Point: 5.0478
>T100257 WP_124371779.1 NZ_CP027761:c4579510-4578935 [Pseudomonas sp. R11-23-07]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLKNRPDLTPDQVDKISALMDKAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPVRVLAAYDIEPMHPDDFISDLWDLDQAAVLAAVQKQRRALVR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLKNRPDLTPDQVDKISALMDKAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPVRVLAAYDIEPMHPDDFISDLWDLDQAAVLAAVQKQRRALVR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML
Download Length: 576 bp
>T100257 NZ_CP027761:c4579510-4578935 [Pseudomonas sp. R11-23-07]
ATGAGGTGTTCGCCTTTCACTGCGGTTTACGACGCCTGTGTTCTGTACCCGGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGTTGTACCGGGCGCGATGGACCCGACAGATTCATGAAGAGTGGAAGCGTAACGTCCTCAAGAACCGAC
CTGATCTCACTCCCGACCAAGTAGATAAAATTTCGGCATTGATGGACAAGGCCATACCGGACGCGTTGGTAACAGGGTAC
GAAGACTTGTGTTCAAGTTTGGATTTGCCTGATCCAGATGATCGTCACGTATTGGCCGCGGCGATTCGGAGTAAGGCGGA
AGTTATCGTGACCTTTAACTTGAAAGATTTTCCAGTGCGGGTACTCGCGGCTTATGACATAGAACCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGACTTGGATCAAGCGGCCGTGTTGGCGGCAGTGCAGAAGCAGAGGCGTGCACTAGTTAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTAGTGCAGACCAGTAAGCTGCTTGGGCCTTA
TGAGGTAATGTTGTAG
ATGAGGTGTTCGCCTTTCACTGCGGTTTACGACGCCTGTGTTCTGTACCCGGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGTTGTACCGGGCGCGATGGACCCGACAGATTCATGAAGAGTGGAAGCGTAACGTCCTCAAGAACCGAC
CTGATCTCACTCCCGACCAAGTAGATAAAATTTCGGCATTGATGGACAAGGCCATACCGGACGCGTTGGTAACAGGGTAC
GAAGACTTGTGTTCAAGTTTGGATTTGCCTGATCCAGATGATCGTCACGTATTGGCCGCGGCGATTCGGAGTAAGGCGGA
AGTTATCGTGACCTTTAACTTGAAAGATTTTCCAGTGCGGGTACTCGCGGCTTATGACATAGAACCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGACTTGGATCAAGCGGCCGTGTTGGCGGCAGTGCAGAAGCAGAGGCGTGCACTAGTTAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTAGTGCAGACCAGTAAGCTGCTTGGGCCTTA
TGAGGTAATGTTGTAG
Antitoxin
Download Length: 157 a.a. Molecular weight: 17689.32 Da Isoelectric Point: 5.6533
>AT100257 WP_124371780.1 NZ_CP027761:c4579977-4579507 [Pseudomonas sp. R11-23-07]
MITNHLPKTIPPLEREVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE
MITNHLPKTIPPLEREVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE
Download Length: 471 bp
>AT100257 NZ_CP027761:c4579977-4579507 [Pseudomonas sp. R11-23-07]
ATGATCACCAATCACCTTCCCAAAACAATTCCTCCGCTGGAGAGGGAAGTCGAAGCCGCTGTGCAAGGCCAACGCGAGCT
GGCTTCGTTGCTATCGACCAAATTCGAAACCCAGCGCATCGACATCTTCGACAAAGAAGACAAGCCTCACACCCTTGTAC
TCCCCACATCCGCGCTGCGCCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGTAATGCCGTCAAAGTTGTACCCGTC
CATGCTGAATTGACCTCTCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGCTGGAAGAAGG
CGCCATTCCCTTTACGAAAACCGGTCGTCATCGGCGTATTCGATTTTCCGATTTGATGGCGTTCAAACAGCGCCGCGATG
AAGAAAGTCAAGAGGCGATGGAGGAACTGGTACGGCAGACCCGGGAGTTGGGATTGGGGTATGACGAATGA
ATGATCACCAATCACCTTCCCAAAACAATTCCTCCGCTGGAGAGGGAAGTCGAAGCCGCTGTGCAAGGCCAACGCGAGCT
GGCTTCGTTGCTATCGACCAAATTCGAAACCCAGCGCATCGACATCTTCGACAAAGAAGACAAGCCTCACACCCTTGTAC
TCCCCACATCCGCGCTGCGCCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGTAATGCCGTCAAAGTTGTACCCGTC
CATGCTGAATTGACCTCTCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGCTGGAAGAAGG
CGCCATTCCCTTTACGAAAACCGGTCGTCATCGGCGTATTCGATTTTCCGATTTGATGGCGTTCAAACAGCGCCGCGATG
AAGAAAGTCAAGAGGCGATGGAGGAACTGGTACGGCAGACCCGGGAGTTGGGATTGGGGTATGACGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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