Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 4578935..4579977 Replicon chromosome
Accession NZ_CP027761
Organism Pseudomonas sp. R11-23-07

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag C4J84_RS20970 Protein ID WP_124371779.1
Coordinates 4578935..4579510 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag C4J84_RS20975 Protein ID WP_124371780.1
Coordinates 4579507..4579977 (-) Length 157 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J84_RS20945 4576349..4576684 + 336 WP_124436024.1 hypothetical protein -
C4J84_RS20950 4576774..4577124 - 351 WP_124405846.1 hypothetical protein -
C4J84_RS20955 4577336..4577665 + 330 WP_124371776.1 hypothetical protein -
C4J84_RS20960 4577673..4578308 - 636 WP_124371777.1 LysE family translocator -
C4J84_RS20965 4578445..4578816 + 372 WP_124371778.1 PH domain-containing protein -
C4J84_RS20970 4578935..4579510 - 576 WP_124371779.1 PIN domain-containing protein Toxin
C4J84_RS20975 4579507..4579977 - 471 WP_124371780.1 helix-turn-helix domain-containing protein Antitoxin
C4J84_RS20980 4580163..4580432 + 270 Protein_4040 detoxification -
C4J84_RS20985 4580485..4580772 + 288 WP_124436025.1 cloacin -
C4J84_RS20990 4580789..4581259 + 471 WP_124436349.1 hypothetical protein -
C4J84_RS20995 4581308..4581682 - 375 WP_124371782.1 cytochrome c family protein -
C4J84_RS21000 4581907..4582287 + 381 WP_124364322.1 response regulator -
C4J84_RS21005 4582481..4583095 + 615 WP_124436026.1 biliverdin-producing heme oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

Helix-turn-helix domain, group 17

(84-132)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21699.18 Da        Isoelectric Point: 5.0478

>T100257 WP_124371779.1 NZ_CP027761:c4579510-4578935 [Pseudomonas sp. R11-23-07]
MRCSPFTAVYDACVLYPAALRDLLMWLGLSGLYRARWTRQIHEEWKRNVLKNRPDLTPDQVDKISALMDKAIPDALVTGY
EDLCSSLDLPDPDDRHVLAAAIRSKAEVIVTFNLKDFPVRVLAAYDIEPMHPDDFISDLWDLDQAAVLAAVQKQRRALVR
PPMNGEGYLEMLMRQGLVQTSKLLGPYEVML

Download         Length: 576 bp

>T100257 NZ_CP027761:c4579510-4578935 [Pseudomonas sp. R11-23-07]
ATGAGGTGTTCGCCTTTCACTGCGGTTTACGACGCCTGTGTTCTGTACCCGGCGGCTCTCAGGGATTTGTTGATGTGGCT
TGGTTTATCCGGGTTGTACCGGGCGCGATGGACCCGACAGATTCATGAAGAGTGGAAGCGTAACGTCCTCAAGAACCGAC
CTGATCTCACTCCCGACCAAGTAGATAAAATTTCGGCATTGATGGACAAGGCCATACCGGACGCGTTGGTAACAGGGTAC
GAAGACTTGTGTTCAAGTTTGGATTTGCCTGATCCAGATGATCGTCACGTATTGGCCGCGGCGATTCGGAGTAAGGCGGA
AGTTATCGTGACCTTTAACTTGAAAGATTTTCCAGTGCGGGTACTCGCGGCTTATGACATAGAACCGATGCATCCCGACG
ACTTTATCTCGGACCTTTGGGACTTGGATCAAGCGGCCGTGTTGGCGGCAGTGCAGAAGCAGAGGCGTGCACTAGTTAGG
CCGCCGATGAATGGGGAAGGGTATCTCGAGATGTTGATGCGGCAGGGGCTAGTGCAGACCAGTAAGCTGCTTGGGCCTTA
TGAGGTAATGTTGTAG

Antitoxin


Download         Length: 157 a.a.        Molecular weight: 17689.32 Da        Isoelectric Point: 5.6533

>AT100257 WP_124371780.1 NZ_CP027761:c4579977-4579507 [Pseudomonas sp. R11-23-07]
MITNHLPKTIPPLEREVEAAVQGQRELASLLSTKFETQRIDIFDKEDKPHTLVLPTSALRLLVDILGELALGNAVKVVPV
HAELTSQEAADLLNVSRPHLVKMLEEGAIPFTKTGRHRRIRFSDLMAFKQRRDEESQEAMEELVRQTRELGLGYDE

Download         Length: 471 bp

>AT100257 NZ_CP027761:c4579977-4579507 [Pseudomonas sp. R11-23-07]
ATGATCACCAATCACCTTCCCAAAACAATTCCTCCGCTGGAGAGGGAAGTCGAAGCCGCTGTGCAAGGCCAACGCGAGCT
GGCTTCGTTGCTATCGACCAAATTCGAAACCCAGCGCATCGACATCTTCGACAAAGAAGACAAGCCTCACACCCTTGTAC
TCCCCACATCCGCGCTGCGCCTGCTGGTTGATATTTTGGGTGAGCTGGCGCTGGGTAATGCCGTCAAAGTTGTACCCGTC
CATGCTGAATTGACCTCTCAGGAAGCTGCCGACCTGCTTAACGTTTCACGCCCGCATCTGGTCAAGATGCTGGAAGAAGG
CGCCATTCCCTTTACGAAAACCGGTCGTCATCGGCGTATTCGATTTTCCGATTTGATGGCGTTCAAACAGCGCCGCGATG
AAGAAAGTCAAGAGGCGATGGAGGAACTGGTACGGCAGACCCGGGAGTTGGGATTGGGGTATGACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References