Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3523066..3524282 Replicon chromosome
Accession NZ_CP027761
Organism Pseudomonas sp. R11-23-07

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J84_RS16070 Protein ID WP_124367567.1
Coordinates 3523710..3524282 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J84_RS16065 Protein ID WP_124371210.1
Coordinates 3523066..3523623 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J84_RS16040 3518778..3519338 - 561 WP_124371206.1 adenine phosphoribosyltransferase -
C4J84_RS16045 3519316..3520287 - 972 WP_124371207.1 cysteine synthase family protein -
C4J84_RS16050 3520779..3521855 + 1077 WP_124371208.1 aldo/keto reductase -
C4J84_RS16055 3521926..3522162 + 237 WP_124363466.1 hypothetical protein -
C4J84_RS16060 3522202..3523032 + 831 WP_124371209.1 acid phosphatase -
C4J84_RS16065 3523066..3523623 + 558 WP_124371210.1 helix-turn-helix domain-containing protein Antitoxin
C4J84_RS16070 3523710..3524282 + 573 WP_124367567.1 HD domain-containing protein Toxin
C4J84_RS16075 3524289..3524711 - 423 WP_124371211.1 RidA family protein -
C4J84_RS16080 3524889..3526472 - 1584 WP_124371212.1 FAD-dependent oxidoreductase -
C4J84_RS16085 3526484..3527407 - 924 WP_124371213.1 ABC transporter substrate-binding protein -
C4J84_RS16090 3527426..3528199 - 774 WP_124435715.1 amino acid ABC transporter ATP-binding protein -
C4J84_RS16095 3528192..3529163 - 972 WP_124430012.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21316.35 Da        Isoelectric Point: 4.9538

>T100256 WP_124367567.1 NZ_CP027761:3523710-3524282 [Pseudomonas sp. R11-23-07]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100256 NZ_CP027761:3523710-3524282 [Pseudomonas sp. R11-23-07]
ATGGACTTCGAAAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20517.54 Da        Isoelectric Point: 10.3561

>AT100256 WP_124371210.1 NZ_CP027761:3523066-3523623 [Pseudomonas sp. R11-23-07]
MPALILQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100256 NZ_CP027761:3523066-3523623 [Pseudomonas sp. R11-23-07]
ATGCCCGCCCTGATACTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCATCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTGGAAGCCGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References