Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 3523066..3524282 | Replicon | chromosome |
Accession | NZ_CP027761 | ||
Organism | Pseudomonas sp. R11-23-07 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | C4J84_RS16070 | Protein ID | WP_124367567.1 |
Coordinates | 3523710..3524282 (+) | Length | 191 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | C4J84_RS16065 | Protein ID | WP_124371210.1 |
Coordinates | 3523066..3523623 (+) | Length | 186 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4J84_RS16040 | 3518778..3519338 | - | 561 | WP_124371206.1 | adenine phosphoribosyltransferase | - |
C4J84_RS16045 | 3519316..3520287 | - | 972 | WP_124371207.1 | cysteine synthase family protein | - |
C4J84_RS16050 | 3520779..3521855 | + | 1077 | WP_124371208.1 | aldo/keto reductase | - |
C4J84_RS16055 | 3521926..3522162 | + | 237 | WP_124363466.1 | hypothetical protein | - |
C4J84_RS16060 | 3522202..3523032 | + | 831 | WP_124371209.1 | acid phosphatase | - |
C4J84_RS16065 | 3523066..3523623 | + | 558 | WP_124371210.1 | helix-turn-helix domain-containing protein | Antitoxin |
C4J84_RS16070 | 3523710..3524282 | + | 573 | WP_124367567.1 | HD domain-containing protein | Toxin |
C4J84_RS16075 | 3524289..3524711 | - | 423 | WP_124371211.1 | RidA family protein | - |
C4J84_RS16080 | 3524889..3526472 | - | 1584 | WP_124371212.1 | FAD-dependent oxidoreductase | - |
C4J84_RS16085 | 3526484..3527407 | - | 924 | WP_124371213.1 | ABC transporter substrate-binding protein | - |
C4J84_RS16090 | 3527426..3528199 | - | 774 | WP_124435715.1 | amino acid ABC transporter ATP-binding protein | - |
C4J84_RS16095 | 3528192..3529163 | - | 972 | WP_124430012.1 | amino acid ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 191 a.a. Molecular weight: 21316.35 Da Isoelectric Point: 4.9538
>T100256 WP_124367567.1 NZ_CP027761:3523710-3524282 [Pseudomonas sp. R11-23-07]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ
Download Length: 573 bp
>T100256 NZ_CP027761:3523710-3524282 [Pseudomonas sp. R11-23-07]
ATGGACTTCGAAAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA
ATGGACTTCGAAAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20517.54 Da Isoelectric Point: 10.3561
>AT100256 WP_124371210.1 NZ_CP027761:3523066-3523623 [Pseudomonas sp. R11-23-07]
MPALILQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL
MPALILQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL
Download Length: 558 bp
>AT100256 NZ_CP027761:3523066-3523623 [Pseudomonas sp. R11-23-07]
ATGCCCGCCCTGATACTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCATCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTGGAAGCCGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA
ATGCCCGCCCTGATACTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCATCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTGGAAGCCGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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