Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/HicA(toxin) |
Location | 2420630..2421243 | Replicon | chromosome |
Accession | NZ_CP027761 | ||
Organism | Pseudomonas sp. R11-23-07 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | C4J84_RS11160 | Protein ID | WP_124370470.1 |
Coordinates | 2420992..2421243 (-) | Length | 84 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | C4J84_RS11155 | Protein ID | WP_124362545.1 |
Coordinates | 2420630..2420995 (-) | Length | 122 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4J84_RS26325 | 2416594..2417838 | + | 1245 | WP_177412745.1 | hypothetical protein | - |
C4J84_RS11145 | 2418063..2419418 | + | 1356 | WP_124362543.1 | MATE family efflux transporter | - |
C4J84_RS11150 | 2419458..2420663 | + | 1206 | WP_124370469.1 | MFS transporter | - |
C4J84_RS11155 | 2420630..2420995 | - | 366 | WP_124362545.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
C4J84_RS11160 | 2420992..2421243 | - | 252 | WP_124370470.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9476.01 Da Isoelectric Point: 10.0459
>T100255 WP_124370470.1 NZ_CP027761:c2421243-2420992 [Pseudomonas sp. R11-23-07]
VSKNEKLLAKLLNEHMAFTWSELVTLLRRLGYTQIEGAGSRVKFDIGDPSALITLHKPHPGNELKHYIRRQIIEQLKSGE
LVQ
VSKNEKLLAKLLNEHMAFTWSELVTLLRRLGYTQIEGAGSRVKFDIGDPSALITLHKPHPGNELKHYIRRQIIEQLKSGE
LVQ
Download Length: 252 bp
>T100255 NZ_CP027761:c2421243-2420992 [Pseudomonas sp. R11-23-07]
GTGTCCAAAAATGAAAAGCTGCTCGCCAAACTGCTCAATGAGCACATGGCATTCACCTGGTCTGAACTCGTAACCCTGTT
ACGGCGACTGGGTTACACACAGATTGAAGGGGCTGGAAGCCGGGTCAAATTCGACATTGGCGACCCCAGTGCACTGATCA
CCTTGCACAAGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAAATCATCGAACAATTGAAATCAGGAGAA
CTGGTTCAGTGA
GTGTCCAAAAATGAAAAGCTGCTCGCCAAACTGCTCAATGAGCACATGGCATTCACCTGGTCTGAACTCGTAACCCTGTT
ACGGCGACTGGGTTACACACAGATTGAAGGGGCTGGAAGCCGGGTCAAATTCGACATTGGCGACCCCAGTGCACTGATCA
CCTTGCACAAGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAAATCATCGAACAATTGAAATCAGGAGAA
CTGGTTCAGTGA
Antitoxin
Download Length: 122 a.a. Molecular weight: 13208.01 Da Isoelectric Point: 6.7400
>AT100255 WP_124362545.1 NZ_CP027761:c2420995-2420630 [Pseudomonas sp. R11-23-07]
VNNQLKHKGYIGSIEASLEDNCLFGKILFIKALVSYEGKTVAELDAAFQEAVDDYLATCQSLGQTPEKPCKGSFNVRVGH
DLHLAAALAANRKKVTLNDLTRQALDEFLHHHFPQPCAATG
VNNQLKHKGYIGSIEASLEDNCLFGKILFIKALVSYEGKTVAELDAAFQEAVDDYLATCQSLGQTPEKPCKGSFNVRVGH
DLHLAAALAANRKKVTLNDLTRQALDEFLHHHFPQPCAATG
Download Length: 366 bp
>AT100255 NZ_CP027761:c2420995-2420630 [Pseudomonas sp. R11-23-07]
GTGAACAACCAGCTGAAACACAAAGGCTACATCGGCTCCATCGAAGCCAGCCTCGAGGACAACTGCCTGTTCGGCAAAAT
CCTGTTCATCAAGGCCCTGGTGAGCTACGAAGGCAAGACTGTCGCAGAGTTGGACGCGGCCTTCCAAGAGGCGGTGGACG
ATTACCTCGCCACCTGCCAGTCGCTCGGGCAAACTCCTGAAAAGCCATGCAAGGGCTCGTTCAACGTACGCGTTGGCCAT
GACCTGCATCTGGCGGCAGCGTTGGCGGCGAACCGCAAGAAAGTGACGTTGAACGACCTGACACGCCAGGCGCTGGATGA
GTTTCTACACCATCATTTCCCGCAGCCTTGCGCGGCGACCGGCTGA
GTGAACAACCAGCTGAAACACAAAGGCTACATCGGCTCCATCGAAGCCAGCCTCGAGGACAACTGCCTGTTCGGCAAAAT
CCTGTTCATCAAGGCCCTGGTGAGCTACGAAGGCAAGACTGTCGCAGAGTTGGACGCGGCCTTCCAAGAGGCGGTGGACG
ATTACCTCGCCACCTGCCAGTCGCTCGGGCAAACTCCTGAAAAGCCATGCAAGGGCTCGTTCAACGTACGCGTTGGCCAT
GACCTGCATCTGGCGGCAGCGTTGGCGGCGAACCGCAAGAAAGTGACGTTGAACGACCTGACACGCCAGGCGCTGGATGA
GTTTCTACACCATCATTTCCCGCAGCCTTGCGCGGCGACCGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|