Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 2420630..2421243 Replicon chromosome
Accession NZ_CP027761
Organism Pseudomonas sp. R11-23-07

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag C4J84_RS11160 Protein ID WP_124370470.1
Coordinates 2420992..2421243 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag C4J84_RS11155 Protein ID WP_124362545.1
Coordinates 2420630..2420995 (-) Length 122 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J84_RS26325 2416594..2417838 + 1245 WP_177412745.1 hypothetical protein -
C4J84_RS11145 2418063..2419418 + 1356 WP_124362543.1 MATE family efflux transporter -
C4J84_RS11150 2419458..2420663 + 1206 WP_124370469.1 MFS transporter -
C4J84_RS11155 2420630..2420995 - 366 WP_124362545.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
C4J84_RS11160 2420992..2421243 - 252 WP_124370470.1 type II toxin-antitoxin system HicA family toxin Toxin

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(20-76)

Antitoxin

(55-105)


Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9476.01 Da        Isoelectric Point: 10.0459

>T100255 WP_124370470.1 NZ_CP027761:c2421243-2420992 [Pseudomonas sp. R11-23-07]
VSKNEKLLAKLLNEHMAFTWSELVTLLRRLGYTQIEGAGSRVKFDIGDPSALITLHKPHPGNELKHYIRRQIIEQLKSGE
LVQ

Download         Length: 252 bp

>T100255 NZ_CP027761:c2421243-2420992 [Pseudomonas sp. R11-23-07]
GTGTCCAAAAATGAAAAGCTGCTCGCCAAACTGCTCAATGAGCACATGGCATTCACCTGGTCTGAACTCGTAACCCTGTT
ACGGCGACTGGGTTACACACAGATTGAAGGGGCTGGAAGCCGGGTCAAATTCGACATTGGCGACCCCAGTGCACTGATCA
CCTTGCACAAGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAAATCATCGAACAATTGAAATCAGGAGAA
CTGGTTCAGTGA

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13208.01 Da        Isoelectric Point: 6.7400

>AT100255 WP_124362545.1 NZ_CP027761:c2420995-2420630 [Pseudomonas sp. R11-23-07]
VNNQLKHKGYIGSIEASLEDNCLFGKILFIKALVSYEGKTVAELDAAFQEAVDDYLATCQSLGQTPEKPCKGSFNVRVGH
DLHLAAALAANRKKVTLNDLTRQALDEFLHHHFPQPCAATG

Download         Length: 366 bp

>AT100255 NZ_CP027761:c2420995-2420630 [Pseudomonas sp. R11-23-07]
GTGAACAACCAGCTGAAACACAAAGGCTACATCGGCTCCATCGAAGCCAGCCTCGAGGACAACTGCCTGTTCGGCAAAAT
CCTGTTCATCAAGGCCCTGGTGAGCTACGAAGGCAAGACTGTCGCAGAGTTGGACGCGGCCTTCCAAGAGGCGGTGGACG
ATTACCTCGCCACCTGCCAGTCGCTCGGGCAAACTCCTGAAAAGCCATGCAAGGGCTCGTTCAACGTACGCGTTGGCCAT
GACCTGCATCTGGCGGCAGCGTTGGCGGCGAACCGCAAGAAAGTGACGTTGAACGACCTGACACGCCAGGCGCTGGATGA
GTTTCTACACCATCATTTCCCGCAGCCTTGCGCGGCGACCGGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References