Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4841608..4842113 Replicon chromosome
Accession NZ_CP027760
Organism Pseudomonas sp. R4-34-07

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4J85_RS22320 Protein ID WP_124408130.1
Coordinates 4841859..4842113 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C4J85_RS22315 Protein ID WP_124368289.1
Coordinates 4841608..4841862 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J85_RS22295 4836815..4837021 + 207 WP_124410722.1 hypothetical protein -
C4J85_RS22300 4837135..4839027 + 1893 WP_124410723.1 alkaline phosphatase family protein -
C4J85_RS22305 4839145..4840158 + 1014 WP_124408128.1 diguanylate cyclase -
C4J85_RS22310 4840264..4841514 + 1251 WP_124410724.1 aspartate aminotransferase family protein -
C4J85_RS22315 4841608..4841862 + 255 WP_124368289.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C4J85_RS22320 4841859..4842113 + 255 WP_124408130.1 Txe/YoeB family addiction module toxin Toxin
C4J85_RS22325 4842216..4842932 + 717 WP_124410725.1 hypothetical protein -
C4J85_RS22330 4842942..4844063 - 1122 WP_124410726.1 aminotransferase class V-fold PLP-dependent enzyme -
C4J85_RS22335 4844065..4845267 - 1203 WP_124371795.1 MFS transporter -
C4J85_RS22340 4845267..4846517 - 1251 WP_124364335.1 ATP-grasp domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10079.60 Da        Isoelectric Point: 7.2746

>T100249 WP_124408130.1 NZ_CP027760:4841859-4842113 [Pseudomonas sp. R4-34-07]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFEGVGKPEPLKHNLSGYWSRRITAEHRLVYGIEEDEVQILMC
RYHY

Download         Length: 255 bp

>T100249 NZ_CP027760:4841859-4842113 [Pseudomonas sp. R4-34-07]
ATGAAAATACTCTTTACCCCTGAGGGCTGGGACGATTATCTGTGGTTTCAACAAAACGACAAGGCAGGGCTCAAGCGTAT
AAACCTGCTCATCAAAGCGATTCAAAGAGACCCATTTGAAGGTGTTGGAAAACCTGAGCCCCTCAAACACAACCTGAGCG
GCTACTGGTCTCGGCGAATCACAGCAGAGCATCGTCTGGTGTATGGCATCGAGGAGGATGAAGTACAGATCCTCATGTGC
CGTTATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9599.97 Da        Isoelectric Point: 6.7262

>AT100249 WP_124368289.1 NZ_CP027760:4841608-4841862 [Pseudomonas sp. R4-34-07]
METINYTHARAHLSETMDRVNEDHIPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRQ
LIEE

Download         Length: 255 bp

>AT100249 NZ_CP027760:4841608-4841862 [Pseudomonas sp. R4-34-07]
ATGGAAACTATCAACTACACCCATGCGCGTGCGCACCTGTCCGAAACCATGGACCGCGTTAATGAAGATCACATTCCACT
GCTCCTGACCCGACAAAAAGGCGAACCGGTGGTGATGATCTCGTTGTCAGAATTCAATGCTCTCGAGGAAACAGCCTATT
TACTGCGCTCGCCAAAAAATGCCGAACGCCTCATCAACTCAGTCAACAGCTTACGAGCCGGCAAAGCCAAGCCAAGGCAG
TTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References