Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3801516..3802732 Replicon chromosome
Accession NZ_CP027760
Organism Pseudomonas sp. R4-34-07

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J85_RS17475 Protein ID WP_124410335.1
Coordinates 3802160..3802732 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J85_RS17470 Protein ID WP_124367566.1
Coordinates 3801516..3802073 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J85_RS17440 3796741..3797406 - 666 WP_124410333.1 hypothetical protein -
C4J85_RS17445 3797399..3798523 - 1125 WP_124410334.1 ThiF family adenylyltransferase -
C4J85_RS17450 3798600..3798704 - 105 WP_124363464.1 pantocin A family RiPP -
C4J85_RS17455 3799226..3800302 + 1077 WP_124371208.1 aldo/keto reductase -
C4J85_RS17460 3800376..3800612 + 237 WP_124363466.1 hypothetical protein -
C4J85_RS17465 3800652..3801482 + 831 WP_124407653.1 acid phosphatase -
C4J85_RS17470 3801516..3802073 + 558 WP_124367566.1 helix-turn-helix domain-containing protein Antitoxin
C4J85_RS17475 3802160..3802732 + 573 WP_124410335.1 HD domain-containing protein Toxin
C4J85_RS17480 3802739..3803161 - 423 WP_124363470.1 RidA family protein -
C4J85_RS17485 3803339..3804922 - 1584 WP_124410336.1 FAD-dependent oxidoreductase -
C4J85_RS17490 3804934..3805857 - 924 WP_124410337.1 ABC transporter substrate-binding protein -
C4J85_RS17495 3805876..3806649 - 774 WP_124410338.1 amino acid ABC transporter ATP-binding protein -
C4J85_RS17500 3806642..3807613 - 972 WP_124367572.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21268.30 Da        Isoelectric Point: 4.9538

>T100246 WP_124410335.1 NZ_CP027760:3802160-3802732 [Pseudomonas sp. R4-34-07]
MDFEKIKGRLDLLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKVLKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100246 NZ_CP027760:3802160-3802732 [Pseudomonas sp. R4-34-07]
ATGGACTTCGAGAAAATCAAAGGCCGCCTCGACCTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCTGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAGTCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGCGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATCCTGACGCTGTGGGATGATTACGAGAACGCGCTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTGTTCGAGGCGCTGCGTGCGCTGATCGACCGGGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20501.50 Da        Isoelectric Point: 10.3561

>AT100246 WP_124367566.1 NZ_CP027760:3801516-3802073 [Pseudomonas sp. R4-34-07]
MPALLPQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100246 NZ_CP027760:3801516-3802073 [Pseudomonas sp. R4-34-07]
ATGCCCGCCCTGCTGCCCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGTTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCACCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTCGAAGCGGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCGGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCGAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References