100241

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 5084340..5086075 Replicon chromosome
Accession NZ_CP027759
Organism Pseudomonas sp. R2-7-07

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4J86_RS23310 Protein ID WP_124371996.1
Coordinates 5084340..5084984 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4J86_RS23315 Protein ID WP_124371997.1
Coordinates 5084981..5086075 (+) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J86_RS23280 5079972..5080499 + 528 WP_003176323.1 inorganic diphosphatase -
C4J86_RS23285 5080710..5081474 + 765 WP_124371993.1 helix-turn-helix transcriptional regulator -
C4J86_RS23295 5081717..5082820 - 1104 WP_124371994.1 DUF91 domain-containing protein -
C4J86_RS23300 5083036..5083271 - 236 Protein_4496 hypothetical protein -
C4J86_RS23305 5083771..5084343 + 573 WP_124371995.1 DUF4433 domain-containing protein -
C4J86_RS23310 5084340..5084984 + 645 WP_124371996.1 DUF4433 domain-containing protein Toxin
C4J86_RS23315 5084981..5086075 + 1095 WP_124371997.1 macro domain-containing protein Antitoxin
C4J86_RS23325 5086261..5087085 - 825 Protein_4500 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
C4J86_RS23330 5087075..5087839 - 765 WP_124371998.1 type IV toxin-antitoxin system AbiEi family antitoxin -
C4J86_RS23335 5088048..5088680 + 633 WP_057724871.1 hydrolase -
C4J86_RS23340 5088742..5089773 - 1032 WP_124371999.1 DUF1016 family protein -
C4J86_RS23350 5089967..5090143 + 177 WP_124372000.1 MerR family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5083036..5095331 12295


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24891.41 Da        Isoelectric Point: 6.4931

>T100241 WP_124371996.1 NZ_CP027759:5084340-5084984 [Pseudomonas sp. R2-7-07]
MIYNNLNPEKALIWRIVHRDNLPWILDNGLHCASSEVQAAQYVNIGNVDLIDKRRTRCVPIAPSGFLSDYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLHRVAELGLPFVFTNAHAYPDWTDYYSDLENLHEIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCYTDAMKERIEQDVAARGLTLPVHARPGWYFP

Download         Length: 645 bp

>T100241 NZ_CP027759:5084340-5084984 [Pseudomonas sp. R2-7-07]
ATGATTTATAACAACCTGAATCCTGAAAAAGCTCTGATCTGGCGAATCGTTCATCGCGACAATCTGCCCTGGATTCTGGA
CAACGGCCTGCACTGCGCCAGCTCAGAGGTGCAGGCTGCGCAATATGTGAACATAGGCAATGTTGATTTAATCGATAAAC
GCCGCACGCGCTGTGTCCCCATTGCTCCTTCAGGCTTTTTGTCAGACTACGTTCCCTTCTATTTCACACCCTTCTCTGTG
ATGATGAAAAATATTCATTCCGGCTGGAGCGTTCAGCAACGCAGCAATGACGAGATCGTGATTCTGGTCTCCAGCCTCCA
CCGCGTCGCCGAGCTTGGCCTACCGTTCGTCTTCACAAATGCACATGCGTACCCGGATTGGACAGACTATTACAGCGACC
TGGAGAATCTCCACGAGATCGATTGGTCTATCCTTCAACGGCGTGACTTCAAACGTGACCCCGATGACCCTCGCAAAATG
GAGCGTTATCAGGCTGAAGCGCTGATTCACCACCACTTACCGATTACAGGACTCCTTGGCATCATGTGTTACACCGATGC
GATGAAAGAACGCATAGAGCAGGACGTCGCCGCAAGAGGCCTGACGTTGCCTGTACATGCTCGTCCGGGATGGTATTTTC
CATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41201.24 Da        Isoelectric Point: 6.2456

>AT100241 WP_124371997.1 NZ_CP027759:5084981-5086075 [Pseudomonas sp. R2-7-07]
MIRFTQGNLLEANTEVLVNTVNTVGVMGKGIALMFKERFAENYRLYAAACKAGEVKTGEVHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWIIEGLHDLRRFLIENHVKSVAVPPLGAGNGGLKWPDVREQIEDVLSDLDVDVLVFEPSNQYLNVAKRNG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKRPGLKNPLDLKFVAHKYGPYANRLEHLLNNLDGSYLH
CDKRISDAENSDVIWFDQDRRAFLQTYLRTEAKEYSQALELTAELIDGFESPFGMELLATVDWLLTQEDVAPTVPALREA
LKQWDGGVAAAARKNKLFDDQALDIALKRLTSSSFSHQMASCHI

Download         Length: 1095 bp

>AT100241 NZ_CP027759:5084981-5086075 [Pseudomonas sp. R2-7-07]
ATGATCAGATTCACTCAGGGTAACCTTCTGGAAGCCAACACCGAAGTCCTCGTCAACACGGTGAATACCGTGGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGTTTTGCAGAAAACTATCGCTTGTACGCTGCTGCCTGTAAAGCTGGCG
AAGTAAAGACCGGAGAAGTGCACGTAACTGCGGTCAACGAACTGGACGGTCCTCGCTGGATCGTTAACTTCCCGACCAAA
CGTCACTGGCGATCACCATCGCAGATGGCATGGATAATCGAAGGCCTGCACGACCTCCGTCGTTTTCTGATTGAAAACCA
TGTGAAGTCGGTGGCGGTTCCTCCGTTAGGGGCCGGTAACGGTGGTCTGAAATGGCCGGACGTTCGCGAACAGATTGAGG
ATGTCTTGAGCGATCTGGATGTCGATGTGTTGGTTTTTGAGCCATCCAATCAGTATCTGAATGTCGCCAAACGCAACGGT
GTAGAAAAGCTTACGCCTGCGCGAGCGCTCATTGCGGAACTGGTTCGACGCTACTGGGTGTTAGGCATGGAATGCAGCCT
GCTTGAGATTCAGAAACTGGCTTGGTTCCTGGAACGCGCAATTGAGAAGCGGCCAGGCCTCAAAAACCCACTGGATCTTA
AATTTGTTGCTCATAAGTACGGGCCGTATGCCAACCGGCTGGAACACCTGCTTAACAATCTGGACGGTAGTTATCTGCAT
TGCGATAAGCGAATCAGCGATGCGGAAAACAGTGATGTGATCTGGTTTGACCAAGACCGCAGAGCCTTTCTACAAACCTA
TCTCAGAACAGAGGCCAAGGAATATTCCCAGGCCTTGGAGCTTACCGCGGAGTTGATTGATGGCTTTGAGTCACCCTTCG
GCATGGAGCTATTGGCAACAGTCGACTGGCTGCTGACCCAGGAAGATGTAGCCCCAACGGTTCCGGCTTTACGTGAGGCA
CTGAAACAATGGGATGGCGGTGTCGCTGCAGCCGCTCGCAAAAACAAGCTGTTTGACGATCAAGCACTTGATATTGCGCT
TAAACGGCTCACTTCCAGCAGCTTCAGCCATCAAATGGCTTCCTGTCATATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References