Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3653837..3655053 Replicon chromosome
Accession NZ_CP027759
Organism Pseudomonas sp. R2-7-07

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J86_RS16660 Protein ID WP_124367567.1
Coordinates 3654481..3655053 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J86_RS16655 Protein ID WP_124371210.1
Coordinates 3653837..3654394 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J86_RS16630 3649549..3650109 - 561 WP_124371206.1 adenine phosphoribosyltransferase -
C4J86_RS16635 3650087..3651058 - 972 WP_124371207.1 cysteine synthase family protein -
C4J86_RS16640 3651550..3652626 + 1077 WP_124371208.1 aldo/keto reductase -
C4J86_RS16645 3652697..3652933 + 237 WP_124363466.1 hypothetical protein -
C4J86_RS16650 3652973..3653803 + 831 WP_124371209.1 acid phosphatase -
C4J86_RS16655 3653837..3654394 + 558 WP_124371210.1 helix-turn-helix domain-containing protein Antitoxin
C4J86_RS16660 3654481..3655053 + 573 WP_124367567.1 HD domain-containing protein Toxin
C4J86_RS16665 3655060..3655482 - 423 WP_124371211.1 RidA family protein -
C4J86_RS16670 3655660..3657243 - 1584 WP_124371212.1 FAD-dependent oxidoreductase -
C4J86_RS16675 3657255..3658178 - 924 WP_124371213.1 ABC transporter substrate-binding protein -
C4J86_RS16680 3658197..3658970 - 774 WP_124371214.1 amino acid ABC transporter ATP-binding protein -
C4J86_RS16685 3658963..3659934 - 972 WP_124367572.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-62)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21316.35 Da        Isoelectric Point: 4.9538

>T100239 WP_124367567.1 NZ_CP027759:3654481-3655053 [Pseudomonas sp. R2-7-07]
MDFEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAINGDIP
AVSQAAFPNKGEQERRDLLQLTQALDGPLKSQILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPLFEALRALIDRATQERLDAAQ

Download         Length: 573 bp

>T100239 NZ_CP027759:3654481-3655053 [Pseudomonas sp. R2-7-07]
ATGGACTTCGAAAAAATCAAAGGCCGCCTCGACTTTCTGCGCGAAGCCGAGAAACTCAAGGACGTGCTCAGAAGCGCCCA
CACCGCTTCGGGACGCACGGAAAGTACCGCCGAACACAGTTGGCGCCTGTGCCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTTAAAATCCTCAAGATGTGCGTGATCCATGACTTGGGCGAAGCCATTAACGGTGACATTCCA
GCAGTCAGCCAGGCGGCGTTTCCCAACAAGGGCGAGCAGGAGCGGCGCGACCTGCTGCAGTTGACCCAAGCCCTGGATGG
GCCCCTGAAAAGCCAGATTCTGACGCTGTGGGATGACTACGAGAACGCACTGTCGCCGGAAGCCAAAGCCGTCAAGGCGA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAGGGCCTCAACCCGCCGGATTTCGATTACGCTTTCAACCTGGCATAC
GGCAAGAAACATACGGATGCCGAGCCCTTATTCGAGGCGCTGCGTGCGCTGATCGACCGCGCTACCCAGGAACGCCTCGA
CGCCGCGCAGTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20517.54 Da        Isoelectric Point: 10.3561

>AT100239 WP_124371210.1 NZ_CP027759:3653837-3654394 [Pseudomonas sp. R2-7-07]
MPALILQPAIPGIALRRWRLLHRVKQTHAAQMFNVNQSTLSRWENGLQAMDAAAHQQLERLLSARLDTAADQALAGLVRD
SSRAVHLVCDLTHRLLACSPSRAAQFSRPLVDLMGQSLWRYATAEIRQVEAALDHTGWRENQAPPALQFSTGSNDSSLVP
IRPSLCRWTRLILSDGSAARLVETL

Download         Length: 558 bp

>AT100239 NZ_CP027759:3653837-3654394 [Pseudomonas sp. R2-7-07]
ATGCCCGCCCTGATACTCCAGCCCGCCATTCCGGGCATTGCGCTGCGCCGATGGCGCCTGTTACACCGCGTCAAGCAAAC
CCATGCCGCACAGATGTTCAACGTAAACCAATCGACGTTGTCCCGCTGGGAGAATGGCCTGCAAGCCATGGACGCTGCCG
CGCATCAACAGCTGGAACGGTTGCTGTCCGCTCGGCTTGACACCGCAGCTGATCAGGCCCTGGCTGGGCTGGTCAGAGAC
AGCTCGCGCGCCGTACACCTGGTGTGCGACCTGACGCACCGCCTCCTGGCCTGTTCGCCCTCCCGCGCCGCCCAGTTCAG
CCGCCCGTTGGTCGACTTGATGGGCCAATCGCTGTGGCGTTATGCGACAGCGGAAATCCGCCAGGTGGAAGCCGCGTTGG
ATCACACCGGCTGGCGCGAGAACCAGGCGCCGCCAGCGCTTCAATTCAGCACCGGCAGCAACGACTCCAGCCTCGTGCCG
ATCCGCCCAAGCCTGTGTCGCTGGACACGCCTGATCCTCAGCGATGGCAGCGCCGCGCGTCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References