Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4112975..4114192 Replicon chromosome
Accession NZ_CP027758
Organism Pseudomonas synxantha strain R2-54-08W

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4J99_RS18365 Protein ID WP_124401235.1
Coordinates 4113620..4114192 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4J99_RS18360 Protein ID WP_124401234.1
Coordinates 4112975..4113532 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J99_RS18345 4108550..4109290 + 741 WP_056846683.1 molecular chaperone -
C4J99_RS18350 4109376..4111886 + 2511 WP_124401232.1 fimbrial biogenesis outer membrane usher protein -
C4J99_RS18355 4111946..4112782 + 837 WP_124401233.1 acid phosphatase -
C4J99_RS18360 4112975..4113532 + 558 WP_124401234.1 helix-turn-helix domain-containing protein Antitoxin
C4J99_RS18365 4113620..4114192 + 573 WP_124401235.1 HD domain-containing protein Toxin
C4J99_RS18370 4114202..4114624 - 423 WP_046068825.1 RidA family protein -
C4J99_RS18375 4114636..4116219 - 1584 WP_124401236.1 FAD-dependent oxidoreductase -
C4J99_RS18380 4116232..4117155 - 924 WP_057024966.1 ABC transporter substrate-binding protein -
C4J99_RS18385 4117174..4117947 - 774 WP_057013589.1 amino acid ABC transporter ATP-binding protein -
C4J99_RS18390 4117940..4118911 - 972 WP_124401237.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-184)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21243.34 Da        Isoelectric Point: 4.9633

>T100231 WP_124401235.1 NZ_CP027758:4113620-4114192 [Pseudomonas synxantha]
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLVLAQSLDSPLKAEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE

Download         Length: 573 bp

>T100231 NZ_CP027758:4113620-4114192 [Pseudomonas synxantha]
ATGGACCTGGAAAAAATCAAAGGCCGTCTCGATTTCCTGCGCGAAGCGGAAAAACTCAAGGATGTGCTCAGAAGTGCCCA
CACGGCTTCGGGTCGCACTGAAAGCACGGCCGAACACAGTTGGCGCCTGTGTCTGATGGCGATGGTGTTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTGAAAATCCTCAAGATGTGCGTTATCCACGATTTGGGCGAAGCCATCCACGGCGATATCCCG
GCGGTCAGCCAGGCAGCCTTTCCCAACAAGGGCGAACAGGAGCGGCTCGACCTGCTGGTGTTGGCGCAGTCCCTGGACAG
CCCCCTGAAAGCCGAGATCCTGACGTTATGGGATGATTACGAGAACGCGCTTTCGCCGGAAGCAAAAGCGGTCAAGGCCA
TGGACAAACTGGAGACCCTGCTGCAGCACACCCAGGGGCTGAACCCTCCCGATTTCGACTACGCCTTCAACCTGGCCTAC
GGCAAAAAACACACGGATGCCGACCCCTTGTTCGAAGCATTGCGGGCATTGATCGATCGAGCGACAGAGCAAAGGCTTCA
CGCCGCCGAGTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20553.53 Da        Isoelectric Point: 8.3363

>AT100231 WP_124401234.1 NZ_CP027758:4112975-4113532 [Pseudomonas synxantha]
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGIQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRARQFSSPLTDLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT100231 NZ_CP027758:4112975-4113532 [Pseudomonas synxantha]
ATGCCTCACTCCTTGCTCAAGCCTGCGCTGCCCGGCATTGCGCTGCGGCGATGGCGTTTGCTGCACCGCGTCAAGCAAAG
CCATGCGGCGCAGTTATTCAACGTCACTCAATCGACTATTTCACGCTGGGAAAGTGGCATACAAGCGATGGATCCGGCTG
CGCACCAACAGCTTGAGCAGCTGTTGGCAGCCCGGCTTGATGCAGCCGCCGACCAGGCATTGGCCCGGTTGGTCAGTGAG
AGTTCGCAAGCGATGCACCTGGTGTGCGACCTGACGCACCGCCTGCTCGCATGCTCGCCTTCCCGCGCACGCCAGTTCAG
CAGCCCGCTCACCGACCTTATGGGCCAGTCGCTGTGGCGCTTCGCAACCCAGGAAATCCAGCTGATCGAAGCCAGCCTGG
AGCACACCGGCTGGCGCGAAACCCAGGCACCCCCAGCCCTTGAGTTCACCACTGGAAGCAACGATTCCAGCCTCGTGCCG
ATACGCCCAAGCCTGTGTCGGTGGACGCGCATGACCCTGAGCGATGGCAGCGCCGCGCGCCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References