Detailed information of TA system TA100226

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 937545..938086
• Replicon: chromosome
• Accession: NZ_CP027758
• Organism: Pseudomonas synxantha strain R2-54-08W

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4J99_RS04165
• Protein ID: WP_164487154.1
• Coordinates: 937811..938086 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A921NKV7
• Locus tag: C4J99_RS04160
• Protein ID: WP_032893597.1
• Coordinates: 937545..937811 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4J99_RS04145	933470..935755	-	2286	WP_124399335.1	TonB-dependent siderophore receptor	-
C4J99_RS04150	935961..936641	+	681	WP_043048515.1	Fe2+-dependent dioxygenase	-
C4J99_RS04155	936643..937401	+	759	WP_124399336.1	sel1 repeat family protein	-
C4J99_RS04160	937545..937811	+	267	WP_032893597.1	ribbon-helix-helix domain-containing protein	Antitoxin
C4J99_RS04165	937811..938086	+	276	WP_164487154.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4J99_RS04170	938150..939313	-	1164	WP_003188470.1	type III PLP-dependent enzyme	-
C4J99_RS04175	939788..940945	-	1158	WP_046070880.1	ABC transporter ATP-binding protein	-
C4J99_RS04180	940942..941595	-	654	WP_034118069.1	ABC transporter permease	-
C4J99_RS04185	941608..942501	-	894	WP_124399338.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-45)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10769.31 Da
• Isoelectric Point: 8.5145

>T100226 WP_164487154.1 NZ_CP027758:937811-938086 [Pseudomonas synxantha]
MELRWTSKALSDLARLYDFLSVVNREAAARIVQSLSQAPDALPGNPRIGERIEEFSPRDVRRLLVGHYEMRYEIQQSTLY
ILRLWHVREDR

Nucleotide

• Length: 276 bp

>T100226 NZ_CP027758:937811-938086 [Pseudomonas synxantha]
ATGGAGCTGAGGTGGACAAGTAAAGCGTTATCCGACCTGGCTCGATTATATGACTTCCTCTCTGTTGTAAACCGCGAAGC
TGCCGCCCGCATCGTGCAGTCACTGTCTCAAGCGCCTGACGCGCTGCCCGGTAATCCGCGCATCGGTGAGAGAATTGAAG
AGTTTTCACCGCGCGACGTAAGAAGACTTTTAGTCGGCCATTACGAAATGCGCTACGAAATTCAACAGTCGACACTTTAT
ATTCTACGGTTATGGCACGTTCGCGAAGATCGTTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9728.00 Da
• Isoelectric Point: 4.7640

>AT100226 WP_032893597.1 NZ_CP027758:937545-937811 [Pseudomonas synxantha]
MGAETKVMTAHIPTALAQKVDQMAARMDRSRGWVVKQALADWVDQEEERSRLTLEAMADVDAGRVIDHQAVQAWADSLST
DSPLPVPR

Nucleotide

• Length: 267 bp

>AT100226 NZ_CP027758:937545-937811 [Pseudomonas synxantha]
ATGGGTGCCGAAACCAAAGTAATGACAGCTCATATTCCCACTGCCCTTGCTCAGAAAGTTGACCAGATGGCCGCGCGAAT
GGATCGATCACGGGGATGGGTGGTGAAACAGGCCCTCGCTGATTGGGTCGATCAAGAAGAAGAGCGCAGCCGGCTGACGC
TTGAGGCTATGGCAGATGTAGATGCGGGGCGCGTGATCGATCACCAGGCAGTGCAGGCCTGGGCAGATAGCCTGAGCACC
GATTCGCCGCTACCGGTACCGCGCTGA