Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4783229..4783793 Replicon chromosome
Accession NZ_CP027757
Organism Pseudomonas synxantha strain R2-4-08W

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4K00_RS21770 Protein ID WP_104505336.1
Coordinates 4783229..4783510 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K00_RS21775 Protein ID WP_057013613.1
Coordinates 4783506..4783793 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K00_RS21750 4780031..4780300 + 270 WP_046069194.1 DUF2790 domain-containing protein -
C4K00_RS21755 4780874..4782124 + 1251 WP_124412926.1 ribonucleotide-diphosphate reductase subunit beta -
C4K00_RS21760 4782199..4782360 + 162 Protein_4203 HNH endonuclease -
C4K00_RS21765 4782433..4783080 + 648 WP_124401646.1 HAD-IB family hydrolase -
C4K00_RS21770 4783229..4783510 - 282 WP_104505336.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K00_RS21775 4783506..4783793 - 288 WP_057013613.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K00_RS21780 4784054..4785013 - 960 WP_124401647.1 LysR family transcriptional regulator -
C4K00_RS21785 4785207..4786634 + 1428 WP_124412927.1 argininosuccinate lyase -
C4K00_RS21790 4786742..4787620 + 879 WP_124401649.1 amino acid ABC transporter permease -
C4K00_RS21795 4787645..4788409 + 765 WP_124401650.1 amino acid ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10944.76 Da        Isoelectric Point: 10.3141

>T100225 WP_104505336.1 NZ_CP027757:c4783510-4783229 [Pseudomonas synxantha]
IEFSIEWDPKALKELKKLDGTIRHQFLRKLQERQDHPRVPADALYGMKDCYKIKLRGAGFRLVYRVEDDRIVILVLAVGK
RERSTVYDSAKSR

Download         Length: 282 bp

>T100225 NZ_CP027757:c4783510-4783229 [Pseudomonas synxantha]
ATTGAGTTTAGTATTGAGTGGGATCCGAAGGCGTTAAAAGAGCTCAAGAAACTGGACGGTACAATTCGTCATCAGTTTTT
GCGCAAACTTCAGGAGCGCCAAGATCACCCGCGGGTTCCAGCGGACGCGCTTTATGGAATGAAGGATTGCTACAAGATCA
AATTACGTGGTGCCGGCTTTCGGCTGGTCTACCGTGTTGAGGACGATCGAATAGTCATCCTCGTATTAGCGGTGGGTAAG
CGGGAACGTAGCACTGTCTACGATTCGGCCAAGAGCCGATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10272.81 Da        Isoelectric Point: 4.3557

>AT100225 WP_057013613.1 NZ_CP027757:c4783793-4783506 [Pseudomonas synxantha]
MQLVLADVAVSVSELKKNPSSVMNGANGSAVAVLNHNRVMGYMVPASVYEAMVERLDELELVQLVKERLDAKEVPIRVSL
DELIAEAEADIANGH

Download         Length: 288 bp

>AT100225 NZ_CP027757:c4783793-4783506 [Pseudomonas synxantha]
ATGCAACTTGTTTTGGCTGACGTGGCCGTCAGCGTATCCGAACTCAAAAAGAACCCTTCATCCGTCATGAACGGAGCCAA
CGGCTCGGCGGTGGCTGTCCTCAACCATAATCGCGTGATGGGTTATATGGTCCCGGCTAGCGTATACGAGGCGATGGTTG
AGCGTCTTGATGAGCTGGAACTGGTGCAATTGGTCAAGGAGAGGTTGGACGCCAAGGAGGTACCGATTCGGGTTTCCCTT
GATGAGCTGATTGCTGAGGCAGAGGCGGATATCGCCAATGGGCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References