Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4179395..4180612 Replicon chromosome
Accession NZ_CP027756
Organism Pseudomonas synxantha strain R6-28-08

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4K01_RS19275 Protein ID WP_046068824.1
Coordinates 4180040..4180612 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4K01_RS19270 Protein ID WP_057024963.1
Coordinates 4179395..4179952 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K01_RS19250 4174466..4175680 + 1215 WP_057024959.1 DUF1835 domain-containing protein -
C4K01_RS19255 4175650..4176231 - 582 WP_124356207.1 hypothetical protein -
C4K01_RS19260 4176330..4178270 + 1941 WP_057024961.1 hypothetical protein -
C4K01_RS19265 4178308..4179144 + 837 WP_057024962.1 acid phosphatase -
C4K01_RS19270 4179395..4179952 + 558 WP_057024963.1 helix-turn-helix domain-containing protein Antitoxin
C4K01_RS19275 4180040..4180612 + 573 WP_046068824.1 HD domain-containing protein Toxin
C4K01_RS19280 4180622..4181044 - 423 WP_057024964.1 RidA family protein -
C4K01_RS19285 4181056..4182639 - 1584 WP_057024965.1 FAD-dependent oxidoreductase -
C4K01_RS19290 4182652..4183575 - 924 WP_057024966.1 ABC transporter substrate-binding protein -
C4K01_RS19295 4183594..4184367 - 774 WP_057013589.1 amino acid ABC transporter ATP-binding protein -
C4K01_RS19300 4184360..4185331 - 972 WP_057024967.1 amino acid ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-184)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21287.39 Da        Isoelectric Point: 4.9633

>T100217 WP_046068824.1 NZ_CP027756:4180040-4180612 [Pseudomonas synxantha]
MDLEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADQLPGLDLLKILKMCVIHDLGEAIHGDIP
AVSQAAFPNKGEQERLDLLLLAQSLDSPLKTEILTLWDDYENALSPEAKAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDADPLFEALRALIDRATEQRLHAAE

Download         Length: 573 bp

>T100217 NZ_CP027756:4180040-4180612 [Pseudomonas synxantha]
ATGGACCTGGAAAAAATCAAAGGCCGTCTCGATTTCCTGCGCGAAGCGGAAAAACTCAAGGATGTGCTCAGAAGCGCCCA
CACGGCTTCGGGTCGCACTGAAAGCACGGCCGAACACAGTTGGCGCCTGTGTCTGATGGCGATGGTATTCGCCGATCAAC
TGCCCGGCCTGGACCTGCTGAAAATCCTCAAGATGTGCGTTATCCATGATTTGGGCGAAGCCATCCACGGCGATATCCCG
GCGGTTAGCCAGGCGGCCTTTCCCAACAAGGGCGAGCAGGAGCGGCTCGACCTGCTGCTGTTGGCCCAGTCCCTGGACAG
TCCGCTGAAAACCGAGATCCTGACGTTGTGGGATGACTACGAGAACGCGCTTTCGCCGGAAGCAAAAGCCGTCAAAGCCA
TGGACAAACTGGAGACCCTGCTGCAGCACACCCAGGGGCTGAACCCTCCCGATTTCGACTACGCCTTCAACCTGGCCTAC
GGCAAAAAACACACGGATGCCGACCCCTTGTTCGAAGCATTGCGGGCATTGATCGATCGAGCGACAGAGCAAAGGCTTCA
CGCCGCCGAGTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20480.48 Da        Isoelectric Point: 7.8770

>AT100217 WP_057024963.1 NZ_CP027756:4179395-4179952 [Pseudomonas synxantha]
MPHSLLKPALPGIALRRWRLLHRVKQSHAAQLFNVTQSTISRWESGVQAMDPAAHQQLEQLLAARLDAAADQALARLVSE
SSQAMHLVCDLTHRLLACSPSRALQFTSPLADLMGQSLWRFATQEIQLIEASLEHTGWRETQAPPALEFTTGSNDSSLVP
IRPSLCRWTRMTLSDGSAARLVETL

Download         Length: 558 bp

>AT100217 NZ_CP027756:4179395-4179952 [Pseudomonas synxantha]
ATGCCTCACTCCTTGCTCAAGCCTGCGCTGCCCGGCATTGCGCTGCGGCGATGGCGTTTGCTGCACCGCGTCAAGCAAAG
CCATGCGGCGCAGCTATTCAACGTCACTCAATCGACTATTTCGCGCTGGGAAAGTGGCGTACAAGCGATGGATCCGGCTG
CGCACCAACAGCTTGAGCAGTTGTTGGCAGCCCGGCTTGATGCAGCCGCCGACCAGGCATTGGCCCGGCTGGTCAGTGAG
AGTTCGCAAGCGATGCACCTGGTGTGCGACCTGACGCACCGCCTGCTCGCATGCTCGCCCTCCCGCGCACTCCAATTCAC
CAGCCCGCTCGCCGATCTTATGGGCCAGTCGCTGTGGCGCTTCGCAACCCAGGAAATCCAGCTGATCGAAGCCAGCCTGG
AACACACCGGCTGGCGCGAAACCCAGGCCCCCCCAGCCCTTGAGTTCACCACTGGAAGCAACGATTCCAGCCTCGTGCCG
ATACGCCCAAGCCTGTGTCGCTGGACACGCATGACCCTGAGCGATGGCAGCGCCGCGCGCCTGGTCGAGACGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References