Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2647177..2647730 Replicon chromosome
Accession NZ_CP027756
Organism Pseudomonas synxantha strain R6-28-08

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag C4K01_RS12265 Protein ID WP_057022653.1
Coordinates 2647437..2647730 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K01_RS12260 Protein ID WP_057022654.1
Coordinates 2647177..2647449 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K01_RS12230 2642407..2642913 + 507 WP_172833441.1 GNAT family N-acetyltransferase -
C4K01_RS12240 2643453..2644391 - 939 WP_057022658.1 GlxA family transcriptional regulator -
C4K01_RS12245 2644564..2645193 + 630 WP_057022657.1 TetR/AcrR family transcriptional regulator -
C4K01_RS12250 2645190..2645867 + 678 WP_057022656.1 type 1 glutamine amidotransferase domain-containing protein -
C4K01_RS12255 2645946..2647073 + 1128 WP_057022655.1 alkene reductase -
C4K01_RS12260 2647177..2647449 + 273 WP_057022654.1 CopG family ribbon-helix-helix protein Antitoxin
C4K01_RS12265 2647437..2647730 + 294 WP_057022653.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K01_RS12270 2647735..2648733 - 999 WP_057022652.1 NAD(P)H-quinone oxidoreductase -
C4K01_RS12275 2648730..2649962 - 1233 WP_057022651.1 YbfB/YjiJ family MFS transporter -
C4K01_RS12280 2650074..2650949 + 876 WP_057022650.1 LysR family transcriptional regulator -
C4K01_RS12285 2651030..2651416 + 387 WP_057022649.1 DoxX family protein -
C4K01_RS12290 2651471..2652289 - 819 WP_057022648.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10844.48 Da        Isoelectric Point: 6.9784

>T100214 WP_057022653.1 NZ_CP027756:2647437-2647730 [Pseudomonas synxantha]
VPRLIITATALAGLERCRQLLTEKDPQVARRAAQTINSQLLRLESDPNIGRPYDELPELRELVIAFGDAGYVALYRVIPS
ESAVLVLAFRHQREAGY

Download         Length: 294 bp

>T100214 NZ_CP027756:2647437-2647730 [Pseudomonas synxantha]
GTGCCACGATTGATCATTACTGCAACGGCGCTGGCAGGCTTAGAACGCTGCCGGCAGCTCTTGACGGAAAAAGATCCGCA
GGTCGCACGCAGGGCCGCCCAGACAATCAATAGCCAGCTGCTCCGTCTGGAATCCGATCCCAATATAGGCCGACCCTATG
ACGAGTTGCCCGAGTTGCGAGAGCTGGTAATCGCTTTCGGGGATGCCGGTTATGTGGCGTTATACCGCGTCATCCCTTCA
GAATCGGCGGTATTGGTATTGGCCTTCCGGCATCAGCGAGAAGCGGGCTACTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10411.61 Da        Isoelectric Point: 6.0787

>AT100214 WP_057022654.1 NZ_CP027756:2647177-2647449 [Pseudomonas synxantha]
MATSIKIDDDLKHRIQLLAGARQRTAHWIMREALSQYVEREEARESFKQEALSSWKNYLETGLHVTGSEARAWLDTWGTE
QASEPPKCHD

Download         Length: 273 bp

>AT100214 NZ_CP027756:2647177-2647449 [Pseudomonas synxantha]
ATGGCAACGTCTATCAAAATCGATGATGACTTGAAGCATCGCATTCAGTTGCTAGCCGGTGCGCGGCAGCGTACCGCTCA
TTGGATTATGCGTGAGGCTCTCTCACAGTATGTGGAGCGAGAAGAGGCACGCGAGAGCTTCAAGCAGGAAGCGTTGTCGT
CTTGGAAGAACTACCTGGAAACGGGCTTGCATGTGACCGGCTCCGAGGCTCGAGCCTGGCTTGACACTTGGGGGACTGAG
CAAGCGTCGGAGCCACCCAAGTGCCACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References