Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 4923571..4924211 Replicon chromosome
Accession NZ_CP027755
Organism Pseudomonas synxantha strain 2-79

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag C4K02_RS22545 Protein ID WP_043050338.1
Coordinates 4923571..4923984 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag C4K02_RS22550 Protein ID WP_043050337.1
Coordinates 4923981..4924211 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K02_RS22530 4919346..4920131 - 786 WP_043050341.1 ABC transporter substrate-binding protein -
C4K02_RS22535 4920791..4922746 - 1956 WP_043050340.1 acetate--CoA ligase -
C4K02_RS22540 4923144..4923413 + 270 WP_043050339.1 DUF2790 domain-containing protein -
C4K02_RS22545 4923571..4923984 - 414 WP_043050338.1 type II toxin-antitoxin system VapC family toxin Toxin
C4K02_RS22550 4923981..4924211 - 231 WP_043050337.1 virulence factor Antitoxin
C4K02_RS22555 4924690..4925940 + 1251 WP_057023889.1 ribonucleotide-diphosphate reductase subunit beta -
C4K02_RS22560 4926015..4926176 + 162 Protein_4331 HNH endonuclease -
C4K02_RS22565 4926249..4926896 + 648 WP_034128477.1 HAD-IB family hydrolase -
C4K02_RS22570 4926995..4927954 - 960 WP_043051157.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15127.45 Da        Isoelectric Point: 7.1890

>T100208 WP_043050338.1 NZ_CP027755:c4923984-4923571 [Pseudomonas synxantha]
VTTYMLDTCICSFIMRERPECVLERLALEVARSNRIVISAITYAEMRYGQIGKKASPKHKTLVDEFVKRLDEVLPWGLAA
VDATVEVKRSLTGQGSIIGQNDTAIAGHAIAAGCTLVTNNVREFSRVAGLSYEDWVH

Download         Length: 414 bp

>T100208 NZ_CP027755:c4923984-4923571 [Pseudomonas synxantha]
GTGACGACATACATGCTGGATACCTGCATTTGCTCATTCATCATGCGTGAACGGCCCGAGTGTGTGCTTGAGCGACTGGC
ATTGGAGGTCGCGAGGAGCAATCGAATCGTGATTTCGGCCATAACCTATGCCGAAATGCGATATGGACAGATTGGGAAAA
AGGCTTCGCCCAAACACAAGACGTTAGTCGATGAGTTTGTGAAGCGGCTCGATGAGGTATTGCCTTGGGGCTTGGCAGCG
GTGGACGCGACGGTTGAGGTGAAGCGAAGCTTGACTGGGCAAGGGTCGATCATCGGTCAAAATGACACGGCGATAGCCGG
GCATGCAATTGCTGCGGGATGTACGTTGGTAACCAACAACGTCCGGGAATTCAGTCGTGTAGCGGGGTTGTCTTACGAGG
ACTGGGTTCACTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8709.77 Da        Isoelectric Point: 4.7719

>AT100208 WP_043050337.1 NZ_CP027755:c4924211-4923981 [Pseudomonas synxantha]
MRTVSIFKNGKNQAIRFPNDMAYEGVGELEITRNGDTITLRPVRPSWGSLRELPKADEDFLQERQDVIGDEGRFNL

Download         Length: 231 bp

>AT100208 NZ_CP027755:c4924211-4923981 [Pseudomonas synxantha]
ATGCGCACAGTCTCGATTTTTAAAAACGGAAAGAACCAGGCTATTCGATTCCCAAACGACATGGCCTATGAGGGAGTCGG
CGAACTCGAAATCACCCGCAACGGAGATACGATTACGTTGCGACCTGTACGACCTAGCTGGGGGTCGTTGCGTGAACTGC
CCAAGGCGGACGAAGATTTTCTACAGGAGCGTCAGGACGTTATTGGCGATGAAGGCAGGTTCAATCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References