100205

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1708073..1708595 Replicon chromosome
Accession NZ_CP027755
Organism Pseudomonas synxantha strain 2-79

Toxin (Protein)


Gene name relE Uniprot ID A0A0D0TMN7
Locus tag C4K02_RS07715 Protein ID WP_043046426.1
Coordinates 1708073..1708366 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0D0RXE7
Locus tag C4K02_RS07720 Protein ID WP_043046427.1
Coordinates 1708356..1708595 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K02_RS07710 1703613..1707758 - 4146 WP_043046424.1 PAS domain S-box protein -
C4K02_RS07715 1708073..1708366 - 294 WP_043046426.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K02_RS07720 1708356..1708595 - 240 WP_043046427.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
C4K02_RS07730 1709247..1709501 + 255 WP_032877263.1 hypothetical protein -
C4K02_RS07735 1709575..1710801 - 1227 WP_032877262.1 MFS transporter -
C4K02_RS07740 1710951..1711889 - 939 WP_043046430.1 LysR family transcriptional regulator -
C4K02_RS07745 1712047..1713363 + 1317 WP_043046432.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-68)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11510.29 Da        Isoelectric Point: 10.0977

>T100205 WP_043046426.1 NZ_CP027755:c1708366-1708073 [Pseudomonas synxantha]
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEVLDNPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVTVFVVAVDK
RERDQAYRKASERLVQR

Download         Length: 294 bp

>T100205 NZ_CP027755:c1708366-1708073 [Pseudomonas synxantha]
ATGACCTATAGCCTTGATTTTGATGCGCGTGCATTGAAGGAATGGCAGAAACTCGGCGACACCCTCCGTCAGCAACTCAA
GAAGAAGCTGGTCGAAGTCCTGGACAACCCACGTATTGAGGCTAACCGCCTACATGGGCTGCCTGACTGCTACAAGATCA
AACTGCGTAGCAGCGGGTACAGGCTGGTGTATCAAGTGATAGATCAGGAAGTTACGGTGTTCGTGGTTGCCGTAGATAAA
CGTGAACGAGATCAAGCTTATCGCAAAGCGTCTGAGCGCCTTGTTCAGCGCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9011.43 Da        Isoelectric Point: 4.6017

>AT100205 WP_043046427.1 NZ_CP027755:c1708595-1708356 [Pseudomonas synxantha]
MASINIRIDDDLKARAYLELEKLGVTPSELIRQALQYVAERGQLPFKPVLMTEEDEALMATVRERLASPQRLRVSLDDL

Download         Length: 240 bp

>AT100205 NZ_CP027755:c1708595-1708356 [Pseudomonas synxantha]
TTGGCATCTATCAACATCCGTATCGATGACGACCTGAAAGCTCGCGCCTACCTTGAGTTGGAGAAACTCGGTGTCACCCC
TTCCGAACTGATACGTCAGGCGTTGCAATATGTTGCCGAACGCGGCCAGTTGCCATTTAAGCCTGTCCTCATGACTGAAG
AGGATGAAGCCTTGATGGCGACCGTACGTGAGCGCCTTGCGTCGCCTCAACGCTTGAGGGTTTCTTTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D0TMN7

Antitoxin

Source ID Structure
AlphaFold DB A0A0D0RXE7

References