Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4476839..4477403 Replicon chromosome
Accession NZ_CP027754
Organism Pseudomonas synxantha strain 30B

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4K03_RS20745 Protein ID WP_124378654.1
Coordinates 4477116..4477403 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K03_RS20740 Protein ID WP_124378653.1
Coordinates 4476839..4477126 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K03_RS20700 4472556..4473035 - 480 WP_124378648.1 hypothetical protein -
C4K03_RS20705 4473910..4474218 + 309 WP_043049590.1 lipoprotein -
C4K03_RS20710 4474582..4474977 - 396 WP_124378649.1 hypothetical protein -
C4K03_RS20715 4475084..4475320 - 237 WP_124378650.1 helix-turn-helix domain-containing protein -
C4K03_RS20720 4475419..4475844 + 426 WP_124378651.1 helix-turn-helix domain-containing protein -
C4K03_RS20735 4476425..4476652 - 228 WP_206433601.1 hypothetical protein -
C4K03_RS20740 4476839..4477126 + 288 WP_124378653.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K03_RS20745 4477116..4477403 + 288 WP_124378654.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K03_RS20750 4477443..4478417 - 975 WP_124378655.1 hypothetical protein -
C4K03_RS20755 4478411..4478767 - 357 WP_124378656.1 hypothetical protein -
C4K03_RS20765 4479203..4479334 - 132 WP_094030725.1 YHYH domain-containing protein -
C4K03_RS20770 4479521..4479742 + 222 WP_043049584.1 hypothetical protein -
C4K03_RS20785 4480409..4480765 - 357 WP_003174972.1 MerR family transcriptional regulator -
C4K03_RS20790 4480746..4481048 - 303 WP_002553164.1 integration host factor subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4470492..4479742 9250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10989.86 Da        Isoelectric Point: 10.2255

>T100202 WP_124378654.1 NZ_CP027754:4477116-4477403 [Pseudomonas synxantha]
MGVEYEVEWDPKALKELRKLDGTIRLQFLKKLQERQAGPRVAGDALHGMKDCYKIKLRGAGYRLVYRVEDERIVILVLAV
GKRERSSVYEQAGKR

Download         Length: 288 bp

>T100202 NZ_CP027754:4477116-4477403 [Pseudomonas synxantha]
ATGGGCGTTGAGTACGAGGTTGAATGGGATCCGAAGGCGCTGAAAGAACTGCGAAAACTCGACGGCACAATCCGCCTCCA
GTTTCTGAAAAAGCTCCAGGAGCGGCAGGCCGGACCTCGGGTGGCAGGCGATGCACTCCACGGCATGAAGGATTGCTACA
AGATCAAATTGCGCGGCGCCGGCTACCGGCTGGTGTATCGCGTTGAGGATGAGCGAATAGTTATCCTGGTGCTGGCTGTC
GGCAAGCGAGAGCGCAGTTCGGTGTACGAGCAGGCAGGGAAACGGTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10237.75 Da        Isoelectric Point: 4.5972

>AT100202 WP_124378653.1 NZ_CP027754:4476839-4477126 [Pseudomonas synxantha]
MQNILADVAVSVSELKKNPSSVLSGANGLPVAVLNHNRVMGYMVPANVYEAMVERLDELELVHLVKGRLDAKETPVRVSL
DDLIGEAEADIANGR

Download         Length: 288 bp

>AT100202 NZ_CP027754:4476839-4477126 [Pseudomonas synxantha]
ATGCAAAATATTCTGGCTGATGTGGCGGTGAGCGTTTCCGAACTCAAGAAGAACCCCTCCTCCGTCTTGAGCGGTGCCAA
CGGCCTGCCCGTGGCCGTACTGAACCACAACCGCGTAATGGGCTACATGGTTCCGGCAAATGTCTACGAAGCGATGGTAG
AGCGCCTGGACGAACTGGAGCTGGTTCACCTGGTCAAGGGTCGTCTCGATGCCAAGGAAACACCTGTTCGAGTATCTCTC
GACGATTTGATTGGCGAGGCCGAGGCAGACATAGCCAATGGGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References