Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE_1-relB/RelE(toxin)
Location 1264615..1265065 Replicon chromosome
Accession NZ_CP027754
Organism Pseudomonas synxantha strain 30B

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag C4K03_RS05815 Protein ID WP_124376455.1
Coordinates 1264793..1265065 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K03_RS05810 Protein ID WP_124376454.1
Coordinates 1264615..1264803 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K03_RS05785 1260182..1261498 + 1317 WP_124376450.1 aromatic acid/H+ symport family MFS transporter -
C4K03_RS05790 1261600..1262403 - 804 WP_124376451.1 tetratricopeptide repeat protein -
C4K03_RS05795 1262591..1263610 + 1020 WP_124376452.1 Glu/Leu/Phe/Val dehydrogenase -
C4K03_RS05800 1263666..1263926 - 261 WP_003188807.1 YebG family protein -
C4K03_RS05805 1264202..1264462 + 261 WP_124376453.1 hypothetical protein -
C4K03_RS05810 1264615..1264803 + 189 WP_124376454.1 antitoxin Antitoxin
C4K03_RS05815 1264793..1265065 + 273 WP_124376455.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K03_RS05820 1265232..1265720 + 489 WP_056845459.1 phosphate-starvation-inducible PsiE family protein -
C4K03_RS05825 1265717..1266034 - 318 WP_124376456.1 DUF3509 domain-containing protein -
C4K03_RS05830 1266355..1267731 - 1377 WP_124376457.1 L-serine ammonia-lyase -
C4K03_RS05835 1267869..1268816 + 948 WP_043048632.1 LysR family transcriptional regulator -
C4K03_RS05840 1269030..1269440 + 411 WP_032877636.1 HPF/RaiA family ribosome-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10576.46 Da        Isoelectric Point: 10.6845

>T100195 WP_124376455.1 NZ_CP027754:1264793-1265065 [Pseudomonas synxantha]
MLIEWVPAARVELRQIIEYISHRNPVAALELKHSIEASVLALSRRPHLYRPGRIIGTREMVVHPNYLVVYKVTDNIRVLS
VLHARQRYPW

Download         Length: 273 bp

>T100195 NZ_CP027754:1264793-1265065 [Pseudomonas synxantha]
ATGCTGATTGAGTGGGTACCCGCAGCGCGGGTGGAACTTCGCCAAATTATTGAATACATCAGTCATCGCAATCCTGTAGC
AGCTCTCGAGTTGAAGCACTCCATCGAAGCCTCGGTGCTGGCCCTCTCTCGCAGACCCCACCTTTACCGTCCTGGCAGAA
TCATTGGTACTCGAGAGATGGTGGTGCATCCGAATTATCTGGTCGTATACAAAGTGACAGACAACATTCGGGTTCTCTCG
GTTTTACACGCACGCCAGCGATATCCTTGGTAG

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6848.47 Da        Isoelectric Point: 4.0061

>AT100195 WP_124376454.1 NZ_CP027754:1264615-1264803 [Pseudomonas synxantha]
MDTSFSSGIQADTEEQADSYDRWFRAKVQAALDDTSPGIPHDEVMAEMQALIESKLKKGDAD

Download         Length: 189 bp

>AT100195 NZ_CP027754:1264615-1264803 [Pseudomonas synxantha]
ATGGACACTTCCTTTTCCTCTGGTATCCAAGCAGATACCGAAGAGCAGGCTGACAGCTACGACCGCTGGTTTCGCGCCAA
GGTGCAGGCCGCTCTTGACGACACCAGCCCCGGCATTCCTCACGACGAGGTGATGGCCGAGATGCAAGCACTGATCGAAT
CCAAACTCAAGAAAGGCGATGCTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References