Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 6209052..6209641 | Replicon | chromosome |
Accession | NZ_CP027753 | ||
Organism | Pseudomonas chlororaphis strain B25 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | C4K04_RS28490 | Protein ID | WP_124322503.1 |
Coordinates | 6209342..6209641 (-) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | C4K04_RS28485 | Protein ID | WP_009045810.1 |
Coordinates | 6209052..6209345 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K04_RS28465 | 6204599..6205762 | - | 1164 | WP_124322500.1 | acyltransferase | - |
C4K04_RS28470 | 6205957..6207147 | - | 1191 | WP_124322501.1 | serine hydrolase | - |
C4K04_RS28475 | 6207274..6208161 | + | 888 | WP_009051074.1 | LysR family transcriptional regulator | - |
C4K04_RS28480 | 6208544..6208936 | + | 393 | WP_124322502.1 | hypothetical protein | - |
C4K04_RS28485 | 6209052..6209345 | - | 294 | WP_009045810.1 | putative addiction module antidote protein | Antitoxin |
C4K04_RS28490 | 6209342..6209641 | - | 300 | WP_124322503.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K04_RS28495 | 6209812..6210261 | + | 450 | WP_124322504.1 | DUF3828 domain-containing protein | - |
C4K04_RS28500 | 6210286..6211296 | - | 1011 | WP_206429860.1 | zinc-binding dehydrogenase | - |
C4K04_RS28505 | 6211354..6211653 | - | 300 | WP_009051080.1 | ArsR family transcriptional regulator | - |
C4K04_RS28510 | 6211718..6212808 | - | 1091 | Protein_5572 | nitrite reductase, copper-containing | - |
C4K04_RS28515 | 6213034..6213276 | + | 243 | WP_007924102.1 | exodeoxyribonuclease VII small subunit | - |
C4K04_RS28520 | 6213273..6214160 | + | 888 | WP_124322506.1 | (2E,6E)-farnesyl diphosphate synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11260.98 Da Isoelectric Point: 10.1871
>T100193 WP_124322503.1 NZ_CP027753:c6209641-6209342 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQCGLQLVILLCGGDKS
RQSRDTELAKYLARRWSRS
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQCGLQLVILLCGGDKS
RQSRDTELAKYLARRWSRS
Download Length: 300 bp
>T100193 NZ_CP027753:c6209641-6209342 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGGGATGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGTGCGGCCTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATACCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATTGC
TGCGCGGATTTTTCGCCTGGCCAACGGCCTTGCCGGGGATGTGTCCCCGGTGGGCGAAGGCGTCAGTGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGGGTTTACTTCCAGCAGTGCGGCCTGCAACTCGTCATCCTGTTGTGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATACCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGTCGATCATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10444.96 Da Isoelectric Point: 5.6642
>AT100193 WP_009045810.1 NZ_CP027753:c6209345-6209052 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS
Download Length: 294 bp
>AT100193 NZ_CP027753:c6209345-6209052 [Pseudomonas chlororaphis]
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGAAAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACGGCGCGGGTGCATGGGGCGTCTTGA
ATGAACGAACCGCTATTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGAAAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGATATGACGGCGCGGGTGCATGGGGCGTCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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