Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2594662..2595247 Replicon chromosome
Accession NZ_CP027753
Organism Pseudomonas chlororaphis strain B25

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K04_RS12050 Protein ID WP_124320163.1
Coordinates 2594954..2595247 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K04_RS12045 Protein ID WP_124320162.1
Coordinates 2594662..2594952 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K04_RS12030 2590007..2592487 + 2481 WP_124320159.1 FtsX-like permease family protein -
C4K04_RS12035 2592477..2593559 + 1083 WP_124320160.1 iron ABC transporter permease -
C4K04_RS12040 2593674..2594261 + 588 WP_124320161.1 hypothetical protein -
C4K04_RS12045 2594662..2594952 - 291 WP_124320162.1 putative addiction module antidote protein Antitoxin
C4K04_RS12050 2594954..2595247 - 294 WP_124320163.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K04_RS12055 2595483..2596877 - 1395 WP_124320164.1 VOC family protein -
C4K04_RS12060 2597141..2598265 + 1125 WP_124320165.1 diguanylate cyclase -
C4K04_RS12065 2598359..2599603 + 1245 WP_124320166.1 M20/M25/M40 family metallo-hydrolase -
C4K04_RS12070 2599840..2600238 + 399 WP_124320167.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(10-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10726.35 Da        Isoelectric Point: 10.7340

>T100192 WP_124320163.1 NZ_CP027753:c2595247-2594954 [Pseudomonas chlororaphis]
MDYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSQMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF

Download         Length: 294 bp

>T100192 NZ_CP027753:c2595247-2594954 [Pseudomonas chlororaphis]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCGATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGTGGTCTCTCGCAGATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCTCGTTCCCTGGCCAAGGAGTTCTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10152.65 Da        Isoelectric Point: 6.9748

>AT100192 WP_124320162.1 NZ_CP027753:c2594952-2594662 [Pseudomonas chlororaphis]
MSDTLVPFDIAALLDGDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIATATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp

>AT100192 NZ_CP027753:c2594952-2594662 [Pseudomonas chlororaphis]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCGCCCTGCTCGACGGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
CGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAACTGTGCACCACCGTGTCCCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References