Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2754976..2756705 Replicon chromosome
Accession NZ_CP027752
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR38

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag C4K05_RS12600 Protein ID WP_124355889.1
Coordinates 2756061..2756705 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag C4K05_RS12595 Protein ID WP_124355888.1
Coordinates 2754976..2756064 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K05_RS12570 2750522..2750932 + 411 WP_124355884.1 hypothetical protein -
C4K05_RS12575 2751056..2752060 + 1005 WP_124355885.1 DUF1016 family protein -
C4K05_RS12580 2752161..2752601 + 441 WP_063429868.1 carboxymuconolactone decarboxylase family protein -
C4K05_RS12585 2752604..2753491 + 888 WP_124355886.1 RNA polymerase sigma factor SigJ -
C4K05_RS31825 2753844..2754605 - 762 WP_124355887.1 HNH endonuclease -
C4K05_RS12595 2754976..2756064 - 1089 WP_124355888.1 macro domain-containing protein Antitoxin
C4K05_RS12600 2756061..2756705 - 645 WP_124355889.1 DUF4433 domain-containing protein Toxin
C4K05_RS12605 2756702..2757274 - 573 WP_124355890.1 DUF4433 domain-containing protein -
C4K05_RS12610 2757464..2757577 - 114 Protein_2453 restriction endonuclease -
C4K05_RS12615 2757690..2758601 - 912 WP_124355891.1 restriction endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24727.21 Da        Isoelectric Point: 6.8256

>T100186 WP_124355889.1 NZ_CP027752:c2756705-2756061 [Pseudomonas chlororaphis subsp. aureofaciens]
MNYSRLNPEKALIWRIVHRDNLPWILDNGLHCASSDVQAPQYVNIGNVDLIDKRRSRHVPIAPGGVLADYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLYRVEQLGLPFVFTNAHAYPDWTDYYSDLANLSQIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCHTDAMKECIEQDVAGRGLALPVHARPGWYFQ

Download         Length: 645 bp

>T100186 NZ_CP027752:c2756705-2756061 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAATTACAGCAGACTGAATCCAGAGAAGGCTCTGATTTGGCGTATCGTCCATCGCGACAATCTGCCTTGGATTCTGGA
CAACGGTCTGCATTGCGCAAGTTCCGACGTACAGGCACCACAATATGTGAACATTGGCAACGTTGACCTGATCGACAAGC
GTCGATCCCGTCATGTGCCCATCGCTCCAGGCGGGGTATTGGCCGATTACGTGCCCTTCTATTTCACCCCCTTCTCTGTG
ATGATGAAAAACATTCACTCTGGATGGAGTGTCCAACAGCGAAGCAACGACGAGATAGTGATTCTGGTCTCAAGTCTGTA
CCGCGTTGAGCAGCTAGGTTTACCGTTTGTCTTCACAAACGCACATGCCTACCCAGATTGGACAGACTATTACAGCGATC
TGGCGAATCTCAGCCAGATCGACTGGTCTATCCTTCAGCGACGTGACTTCAAACGCGACCCTGATGACCCTCGAAAAATG
GAGCGCTATCAGGCTGAAGCGCTGATTCACCATCACCTACCTATTACAGGACTCCTTGGCATCATGTGCCACACCGATGC
AATGAAAGAATGCATAGAACAAGACGTGGCCGGCAGAGGGTTGGCCTTACCTGTTCATGCCCGTCCGGGATGGTATTTCC
AATGA

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40680.81 Da        Isoelectric Point: 7.0978

>AT100186 WP_124355888.1 NZ_CP027752:c2756064-2754976 [Pseudomonas chlororaphis subsp. aureofaciens]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAENYRLYSAACKAGEVETGKMHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWVTEGLHDLRRFLIENQVRSVAVPPLGAGNGGLKWPEVREQIVTVLSDLDVDILVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIEKLPATENPLNLKFVAHKYGPYANRLDHLLNNLDGSYLH
CNKRISDAGISDVIWFDEERKAFLQTYLKTEAKEYSQALEHTAKLIDGFESPFGMELLATVDWLLSQEGISPTVPAVRDA
LKNWDGGAGAAARKSRLFDNQALDIALKRLTSSSFMPEMATC

Download         Length: 1089 bp

>AT100186 NZ_CP027752:c2756064-2754976 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCCGATTTACCCAAGGCAACCTTCTGGAAGCCAAAACCGAAGCTCTGGTCAACACGGTGAATACCGTAGGCGTGAT
GGGCAAAGGTATCGCGCTGATGTTTAAAGAGCGCTTTGCTGAAAATTACCGTCTGTACTCAGCTGCCTGTAAGGCGGGCG
AAGTGGAGACAGGCAAAATGCACGTGACAGCAGTCAACGAGCTGGACGGGCCTCGCTGGATCGTGAACTTCCCAACCAAA
CGTCACTGGCGATCGCCGTCGCAGATGGCTTGGGTGACGGAGGGTTTGCATGATTTACGTCGTTTCTTGATTGAAAACCA
AGTGAGGTCAGTAGCGGTTCCACCACTAGGCGCCGGTAATGGTGGCTTAAAATGGCCTGAAGTTCGCGAACAGATCGTCA
CCGTATTGAGTGACCTGGATGTGGACATTCTGGTGTTCGAGCCCTCCAATCAGTATTTGAATGTCGCCAAACGTAGCGGT
GTGGAAAAGCTAACACCTGCTCGTGCCCTAATTGCCGAACTGGTTCGACGCTATTGGGTTTTAGGTATGGAATGCAGCCT
GCTTGAGATTCAGAAACTAGCCTGGTTTCTTGAGCGAGCTATAGAAAAGCTACCGGCCACAGAAAACCCATTGAACCTTA
AATTTGTGGCTCATAAGTACGGGCCGTACGCCAACAGATTGGACCATCTACTCAACAATCTGGATGGGAGTTATCTGCAT
TGCAACAAACGCATCAGCGATGCAGGTATCAGTGATGTGATCTGGTTTGATGAAGAGCGCAAAGCCTTTCTGCAAACCTA
TCTCAAGACAGAAGCCAAGGAGTACTCACAAGCTCTGGAGCATACTGCCAAGCTAATTGATGGCTTTGAGTCCCCCTTCG
GTATGGAGTTGTTGGCAACAGTCGATTGGTTGCTGAGTCAGGAAGGGATTTCTCCAACTGTTCCTGCCGTACGCGACGCG
TTGAAAAATTGGGATGGCGGAGCCGGTGCTGCTGCCCGAAAAAGCAGGCTGTTCGACAATCAGGCGCTTGATATCGCACT
CAAACGCCTGACCTCAAGTAGTTTCATGCCTGAAATGGCTACCTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References