Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 2460908..2461493 | Replicon | chromosome |
Accession | NZ_CP027752 | ||
Organism | Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR38 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | A0A7S5HMS4 |
Locus tag | C4K05_RS11305 | Protein ID | WP_016705075.1 |
Coordinates | 2461200..2461493 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A8A9ZIA4 |
Locus tag | C4K05_RS11300 | Protein ID | WP_009048177.1 |
Coordinates | 2460908..2461198 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K05_RS11290 | 2458420..2459802 | + | 1383 | WP_009048175.1 | efflux transporter outer membrane subunit | - |
C4K05_RS11295 | 2459921..2460508 | + | 588 | WP_028682910.1 | hypothetical protein | - |
C4K05_RS11300 | 2460908..2461198 | - | 291 | WP_009048177.1 | putative addiction module antidote protein | Antitoxin |
C4K05_RS11305 | 2461200..2461493 | - | 294 | WP_016705075.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K05_RS11310 | 2461728..2463122 | - | 1395 | WP_053268635.1 | VOC family protein | - |
C4K05_RS11315 | 2463387..2464511 | + | 1125 | WP_041988396.1 | diguanylate cyclase | - |
C4K05_RS11320 | 2464605..2465849 | + | 1245 | WP_124301305.1 | M20/M25/M40 family metallo-hydrolase | - |
C4K05_RS11325 | 2466088..2466486 | + | 399 | WP_110175421.1 | carboxymuconolactone decarboxylase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10699.27 Da Isoelectric Point: 10.0959
>T100185 WP_016705075.1 NZ_CP027752:c2461493-2461200 [Pseudomonas chlororaphis subsp. aureofaciens]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF
Download Length: 294 bp
>T100185 NZ_CP027752:c2461493-2461200 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCGTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCGTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10279.84 Da Isoelectric Point: 8.0096
>AT100185 WP_009048177.1 NZ_CP027752:c2461198-2460908 [Pseudomonas chlororaphis subsp. aureofaciens]
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
Download Length: 291 bp
>AT100185 NZ_CP027752:c2461198-2460908 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGACGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGCCCCGAGGCTGA
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGACGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGCCCCGAGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7S5HMS4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8A9ZIA4 |