Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 2352158..2352743 | Replicon | chromosome |
Accession | NZ_CP027751 | ||
Organism | Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR18 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | A0A7S5HMS4 |
Locus tag | C4K06_RS10775 | Protein ID | WP_016705075.1 |
Coordinates | 2352450..2352743 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A8A9ZIA4 |
Locus tag | C4K06_RS10770 | Protein ID | WP_009048177.1 |
Coordinates | 2352158..2352448 (-) | Length | 97 a.a. |
Genomic Context
Location: 2349670..2351052 (1383 bp)
Type: Others
Protein ID: WP_009048175.1
Type: Others
Protein ID: WP_009048175.1
Location: 2351171..2351758 (588 bp)
Type: Others
Protein ID: WP_028682910.1
Type: Others
Protein ID: WP_028682910.1
Location: 2354637..2355761 (1125 bp)
Type: Others
Protein ID: WP_041988396.1
Type: Others
Protein ID: WP_041988396.1
Location: 2352158..2352448 (291 bp)
Type: Antitoxin
Protein ID: WP_009048177.1
Type: Antitoxin
Protein ID: WP_009048177.1
Location: 2352450..2352743 (294 bp)
Type: Toxin
Protein ID: WP_016705075.1
Type: Toxin
Protein ID: WP_016705075.1
Location: 2352978..2354372 (1395 bp)
Type: Others
Protein ID: WP_053268635.1
Type: Others
Protein ID: WP_053268635.1
Location: 2356034..2356459 (426 bp)
Type: Others
Protein ID: WP_124303536.1
Type: Others
Protein ID: WP_124303536.1
Location: 2356473..2357540 (1068 bp)
Type: Others
Protein ID: WP_124303538.1
Type: Others
Protein ID: WP_124303538.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K06_RS10760 | 2349670..2351052 | + | 1383 | WP_009048175.1 | efflux transporter outer membrane subunit | - |
C4K06_RS10765 | 2351171..2351758 | + | 588 | WP_028682910.1 | hypothetical protein | - |
C4K06_RS10770 | 2352158..2352448 | - | 291 | WP_009048177.1 | putative addiction module antidote protein | Antitoxin |
C4K06_RS10775 | 2352450..2352743 | - | 294 | WP_016705075.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K06_RS10780 | 2352978..2354372 | - | 1395 | WP_053268635.1 | VOC family protein | - |
C4K06_RS10785 | 2354637..2355761 | + | 1125 | WP_041988396.1 | diguanylate cyclase | - |
C4K06_RS10790 | 2356034..2356459 | - | 426 | WP_124303536.1 | tail fiber assembly protein | - |
C4K06_RS10795 | 2356473..2357540 | - | 1068 | WP_124303538.1 | hypothetical protein | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2352158..2391149 | 38991 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10699.27 Da Isoelectric Point: 10.0959
>T100177 WP_016705075.1 NZ_CP027751:c2352743-2352450 [Pseudomonas chlororaphis subsp. aureofaciens]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF
Download Length: 294 bp
>T100177 NZ_CP027751:c2352743-2352450 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCGTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
ATGGATTACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCACACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCGTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATACAGGCGCCGGCTACCGCCTCTATTTCACGGTTCGCGGCAATACCCTCATCGTCCTGCTGCTGGGTGGCGACAAG
TCCAGCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10279.84 Da Isoelectric Point: 8.0096
>AT100177 WP_009048177.1 NZ_CP027751:c2352448-2352158 [Pseudomonas chlororaphis subsp. aureofaciens]
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
Download Length: 291 bp
>AT100177 NZ_CP027751:c2352448-2352158 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGACGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGCCCCGAGGCTGA
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGACGAACTGATCCGCGCCCTGGGCCACGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGACCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCTTTTGCCCCGGGGGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGCTGTGCACCACCGTGCCCCGAGGCTGA
Structures
Toxin
Loading, please wait
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7S5HMS4 |
Antitoxin
Loading, please wait
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A8A9ZIA4 |