Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6135020..6135609 Replicon chromosome
Accession NZ_CP027750
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzS24

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K07_RS27740 Protein ID WP_053270039.1
Coordinates 6135310..6135609 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K07_RS27735 Protein ID WP_028683469.1
Coordinates 6135020..6135313 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K07_RS27715 6130561..6131724 - 1164 WP_124302191.1 acyltransferase -
C4K07_RS27720 6131919..6133109 - 1191 WP_124302192.1 serine hydrolase -
C4K07_RS27725 6133236..6134123 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K07_RS27730 6134495..6134887 + 393 WP_009051075.1 hypothetical protein -
C4K07_RS27735 6135020..6135313 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
C4K07_RS27740 6135310..6135609 - 300 WP_053270039.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K07_RS27745 6135780..6136229 + 450 WP_124302193.1 DUF3828 domain-containing protein -
C4K07_RS27750 6136254..6137264 - 1011 WP_173424526.1 NAD(P)-dependent alcohol dehydrogenase -
C4K07_RS27755 6137322..6137621 - 300 WP_009051080.1 ArsR family transcriptional regulator -
C4K07_RS27760 6137685..6138776 - 1092 WP_009051081.1 nitrite reductase, copper-containing -
C4K07_RS27765 6139002..6139244 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K07_RS27770 6139241..6140128 + 888 WP_124302194.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11267.01 Da        Isoelectric Point: 10.4277

>T100172 WP_053270039.1 NZ_CP027750:c6135609-6135310 [Pseudomonas chlororaphis subsp. aureofaciens]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

>T100172 NZ_CP027750:c6135609-6135310 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGAGTTTATTTCCAGCAGCTTGGTTCGCAACTTGTCATTTTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT100172 WP_028683469.1 NZ_CP027750:c6135313-6135020 [Pseudomonas chlororaphis subsp. aureofaciens]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT100172 NZ_CP027750:c6135313-6135020 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References