Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6299201..6299790 Replicon chromosome
Accession NZ_CP027749
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR39

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag C4K08_RS28465 Protein ID WP_053270039.1
Coordinates 6299491..6299790 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag C4K08_RS28460 Protein ID WP_028683469.1
Coordinates 6299201..6299494 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K08_RS28440 6294743..6295927 - 1185 WP_124345204.1 acyltransferase -
C4K08_RS28445 6296100..6297290 - 1191 WP_028683472.1 serine hydrolase -
C4K08_RS28450 6297417..6298304 + 888 WP_009051074.1 LysR family transcriptional regulator -
C4K08_RS28455 6298676..6299068 + 393 WP_009051075.1 hypothetical protein -
C4K08_RS28460 6299201..6299494 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
C4K08_RS28465 6299491..6299790 - 300 WP_053270039.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K08_RS28470 6299961..6300410 + 450 WP_124302193.1 DUF3828 domain-containing protein -
C4K08_RS28475 6300435..6301445 - 1011 WP_173424526.1 NAD(P)-dependent alcohol dehydrogenase -
C4K08_RS28480 6301503..6301802 - 300 WP_009051080.1 ArsR family transcriptional regulator -
C4K08_RS28485 6301866..6302956 - 1091 Protein_5563 nitrite reductase, copper-containing -
C4K08_RS28490 6303182..6303424 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
C4K08_RS28495 6303421..6304308 + 888 WP_124302194.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11267.01 Da        Isoelectric Point: 10.4277

>T100164 WP_053270039.1 NZ_CP027749:c6299790-6299491 [Pseudomonas chlororaphis subsp. aureofaciens]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

>T100164 NZ_CP027749:c6299790-6299491 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGAGTTTATTTCCAGCAGCTTGGTTCGCAACTTGTCATTTTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT100164 WP_028683469.1 NZ_CP027749:c6299494-6299201 [Pseudomonas chlororaphis subsp. aureofaciens]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT100164 NZ_CP027749:c6299494-6299201 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References