100158

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 201537..202053 Replicon chromosome
Accession NZ_CP027749
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR39

Toxin (Protein)


Gene name stbE Uniprot ID A0A8A9Z863
Locus tag C4K08_RS00865 Protein ID WP_028681510.1
Coordinates 201772..202053 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag C4K08_RS00860 Protein ID WP_009046356.1
Coordinates 201537..201782 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K08_RS00835 197306..198301 + 996 WP_041985268.1 aspartyl beta-hydroxylase -
C4K08_RS00840 198267..199025 - 759 WP_009046352.1 slipin family protein -
C4K08_RS00845 199027..200412 - 1386 WP_009046353.1 nodulation protein NfeD -
C4K08_RS00850 200636..201097 + 462 WP_016705004.1 YbaK/EbsC family protein -
C4K08_RS00855 201228..201503 + 276 WP_124312601.1 DUF2789 domain-containing protein -
C4K08_RS00860 201537..201782 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K08_RS00865 201772..202053 + 282 WP_028681510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K08_RS00870 202186..202614 + 429 WP_009046358.1 winged helix DNA-binding protein -
C4K08_RS00875 202611..204694 + 2084 Protein_167 FUSC family protein -
C4K08_RS00880 204691..204900 + 210 WP_025808541.1 DUF1656 domain-containing protein -
C4K08_RS00885 204897..205790 + 894 WP_124310053.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10907.82 Da        Isoelectric Point: 10.6258

>T100158 WP_028681510.1 NZ_CP027749:201772-202053 [Pseudomonas chlororaphis subsp. aureofaciens]
MTYKLQFLPSARKEWDKLGHTLREQFKRKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

>T100158 NZ_CP027749:201772-202053 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGACTTATAAGCTCCAGTTCCTGCCTTCGGCGCGCAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAGGAAGCTGGCCGAGCGCCTGGAAATGCCGCGGGTGCCCGCGGACGCCCTTCACGGTATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTCGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGTGCCGTGTATGAGCGGGCCCGAAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT100158 WP_009046356.1 NZ_CP027749:201537-201782 [Pseudomonas chlororaphis subsp. aureofaciens]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp

>AT100158 NZ_CP027749:201537-201782 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAATCCTTCGGCTGTCCTGAACGGCGCACA
GGGTGGTGCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGTCACGAGACCCCGGTCCCGGTAAATCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8A9Z863

Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References