Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5811189..5811817 Replicon chromosome
Accession NZ_CP027746
Organism Pseudomonas chlororaphis subsp. aurantiaca strain DSM 19603

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag C4K17_RS26155 Protein ID WP_038576104.1
Coordinates 5811189..5811587 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag C4K17_RS26160 Protein ID WP_081359896.1
Coordinates 5811587..5811817 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K17_RS26130 5806427..5806702 + 276 WP_038576112.1 hypothetical protein -
C4K17_RS32570 5806909..5807085 + 177 WP_164486677.1 hypothetical protein -
C4K17_RS26135 5807290..5807787 + 498 WP_081363157.1 PAAR domain-containing protein -
C4K17_RS26140 5807791..5808525 + 735 WP_081359899.1 alpha/beta hydrolase -
C4K17_RS26145 5808522..5809046 + 525 WP_081359898.1 hypothetical protein -
C4K17_RS26150 5809182..5811131 + 1950 WP_081359897.1 alkaline phosphatase family protein -
C4K17_RS26155 5811189..5811587 - 399 WP_038576104.1 tRNA(fMet)-specific endonuclease VapC Toxin
C4K17_RS26160 5811587..5811817 - 231 WP_081359896.1 antitoxin Antitoxin
C4K17_RS26165 5812095..5813072 + 978 WP_081359895.1 type I-F CRISPR-associated endonuclease Cas1 -
C4K17_RS26170 5813069..5816485 + 3417 WP_081359894.1 type I-F CRISPR-associated helicase Cas3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14886.17 Da        Isoelectric Point: 7.2433

>T100149 WP_038576104.1 NZ_CP027746:c5811587-5811189 [Pseudomonas chlororaphis subsp. aurantiaca]
MLKYMLDTNICIFTIKNKPERVREAFNRQHGRLCISSVTLMELIYGAEKSAAPERNLSVIEGFVARLEVLAYDYEAAIHS
GQLRAELARAGTPIGPYDQLIAGHARSQGLVLVTNNVREFERVPGLRIEDWL

Download         Length: 399 bp

>T100149 NZ_CP027746:c5811587-5811189 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGCTCAAGTACATGTTGGATACGAACATCTGTATTTTCACCATCAAGAACAAACCGGAGCGGGTTCGGGAGGCGTTCAA
CCGCCAGCACGGCCGGTTGTGCATCAGTTCGGTGACCTTGATGGAACTGATTTATGGAGCAGAAAAATCAGCGGCTCCTG
AGAGAAACCTGTCTGTCATAGAGGGCTTCGTGGCACGTCTGGAAGTGCTCGCGTATGACTACGAAGCTGCTATTCACAGC
GGTCAGTTGCGTGCCGAGTTGGCCAGGGCTGGTACGCCAATAGGTCCTTACGATCAGCTGATTGCCGGCCATGCCAGATC
CCAGGGATTGGTATTGGTGACCAACAATGTGCGCGAGTTTGAACGGGTGCCAGGGCTGCGTATTGAGGATTGGCTCTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8514.44 Da        Isoelectric Point: 4.2821

>AT100149 WP_081359896.1 NZ_CP027746:c5811817-5811587 [Pseudomonas chlororaphis subsp. aurantiaca]
MEQGSVFKSNRSQAIRMPKAVALPDDVTRVDIVAVGRTRIITPAGEAWDSWFDGESVSADFMNERDQPAEQEREAF

Download         Length: 231 bp

>AT100149 NZ_CP027746:c5811817-5811587 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGGAACAAGGGTCGGTATTCAAAAGTAACCGCAGCCAGGCCATTCGAATGCCCAAGGCAGTGGCTCTCCCTGACGATGT
AACGCGGGTGGATATCGTTGCGGTAGGGCGTACCCGGATCATTACCCCGGCGGGGGAAGCCTGGGACAGCTGGTTCGATG
GCGAGTCGGTGAGCGCGGACTTCATGAATGAGCGGGATCAGCCTGCGGAACAAGAGCGTGAGGCGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References