Detailed information of TA system TA100138

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1043249..1043787
• Replicon: chromosome
• Accession: NZ_CP027744
• Organism: Pseudomonas chlororaphis subsp. aurantiaca strain M71

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: C4K19_RS04750
• Protein ID: WP_016701683.1
• Coordinates: 1043509..1043787 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: C4K19_RS04745
• Protein ID: WP_124310362.1
• Coordinates: 1043249..1043512 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C4K19_RS04730	1039240..1041513	-	2274	WP_124310359.1	TonB-dependent siderophore receptor	-
C4K19_RS04735	1041719..1042399	+	681	WP_124310360.1	Fe2+-dependent dioxygenase	-
C4K19_RS04740	1042403..1043188	+	786	WP_124310361.1	sel1 repeat family protein	-
C4K19_RS04745	1043249..1043512	+	264	WP_124310362.1	ribbon-helix-helix domain-containing protein	Antitoxin
C4K19_RS04750	1043509..1043787	+	279	WP_016701683.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
C4K19_RS04755	1043862..1045025	-	1164	WP_025806386.1	type III PLP-dependent enzyme	-
C4K19_RS04760	1045610..1046767	-	1158	WP_009046959.1	ABC transporter ATP-binding protein	-
C4K19_RS04765	1046990..1047682	-	693	WP_124310363.1	ABC transporter permease	-
C4K19_RS04770	1047697..1048590	-	894	WP_124310364.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-44)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10881.51 Da
• Isoelectric Point: 9.6914

>T100138 WP_016701683.1 NZ_CP027744:1043509-1043787 [Pseudomonas chlororaphis subsp. aurantiaca]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIRDATL
YILRVWHVREDR

Nucleotide

• Length: 279 bp

>T100138 NZ_CP027744:1043509-1043787 [Pseudomonas chlororaphis subsp. aurantiaca]
GTGAGGGAATTGAAATGGACGAGCAAGGCGCTGTCGGACCTGGCCCGACTGTTTGAGTTTCTTGCTCCGGTGAACCGTTC
GGTGGCTGCTCGAACGGTGCAATCGCTCACACAGGCCCCGGATACCCTGCTGACCAATCCGCGTATCGGCGAACAGTTGG
AGGAGTTTCAGCCTCGCGATGTTCGGCGTTTATTGGTCGGGCCTTACGAGATGCGTTACGAGATCCGGGATGCGACGCTC
TACATCCTGCGGGTGTGGCATGTACGAGAAGACCGCTAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9722.09 Da
• Isoelectric Point: 5.5440

>AT100138 WP_124310362.1 NZ_CP027744:1043249-1043512 [Pseudomonas chlororaphis subsp. aurantiaca]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGHVIDHQAVQAWAESLMSD
KPLPVPK

Nucleotide

• Length: 264 bp

>AT100138 NZ_CP027744:1043249-1043512 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGACCGCAACTAAAGTGCTGACCGCACATGTGCCGTTGGAGTTGGCCGACAAGGTCGACCAGATGGCCTCCCGGCTGGA
GCGCTCGCGCGGCTGGATCGTCAAGCAGGCTCTGGTGGCTTGGGTCGATCAGGAAGAGGAGCGTAGTCGCCTGACCCATG
AGGCTTTGGCCGATGTGGATGCTGGGCATGTCATCGATCACCAGGCTGTCCAGGCATGGGCTGAAAGCCTGATGAGTGAC
AAGCCTTTGCCGGTGCCCAAGTGA