Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4271914..4272433 Replicon chromosome
Accession NZ_CP027742
Organism Pseudomonas chlororaphis subsp. aurantiaca strain 464

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag C4K21_RS19060 Protein ID WP_081360541.1
Coordinates 4271914..4272195 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag C4K21_RS19065 Protein ID WP_124335133.1
Coordinates 4272185..4272433 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K21_RS19035 4267503..4267775 + 273 WP_081360544.1 hypothetical protein -
C4K21_RS19045 4268442..4269233 + 792 WP_124335132.1 methyltransferase domain-containing protein -
C4K21_RS19050 4269548..4270030 + 483 WP_009049637.1 acyl-CoA thioesterase -
C4K21_RS19055 4270087..4271736 + 1650 WP_081360542.1 FMN-binding glutamate synthase family protein -
C4K21_RS19060 4271914..4272195 - 282 WP_081360541.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C4K21_RS19065 4272185..4272433 - 249 WP_124335133.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
C4K21_RS19070 4272529..4273317 - 789 WP_124299848.1 helix-turn-helix transcriptional regulator -
C4K21_RS19075 4273402..4274400 + 999 WP_124335134.1 bile acid:sodium symporter -
C4K21_RS19080 4274615..4276378 + 1764 WP_124335135.1 hypothetical protein -
C4K21_RS19085 4276451..4276912 + 462 WP_009049642.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10821.62 Da        Isoelectric Point: 10.5816

>T100127 WP_081360541.1 NZ_CP027742:c4272195-4271914 [Pseudomonas chlororaphis subsp. aurantiaca]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQASKR

Download         Length: 282 bp

>T100127 NZ_CP027742:c4272195-4271914 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGACTTATGAGCTGGAGTTCTCCGAGAAAGCCTGGAAGGAATGGCAAAAGCTGGGCCCCACGCTGAAAGAGCAATTCAA
GAAGAAGCTGCAGGAAAGACTCGTCAACCCCCATGTCCCGGCCGATCGCCTGAGCGGTTTGGGCAATGCCTACAAAATCA
AACTGCGCACGGCGGGCTACCGCCTGGTGTATCGGGTGGTGGATGAGGTGTTGGTGGTGACGGTCATTGCCGTGGGCAAG
CGAGAGCGGGGGAGTGTCTATCAGCAAGCCAGCAAGCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8987.34 Da        Isoelectric Point: 4.4142

>AT100127 WP_124335133.1 NZ_CP027742:c4272433-4272185 [Pseudomonas chlororaphis subsp. aurantiaca]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDSTIKVSLD
DL

Download         Length: 249 bp

>AT100127 NZ_CP027742:c4272433-4272185 [Pseudomonas chlororaphis subsp. aurantiaca]
ATGACCCATGTCCTTCTGTCCAACGTCGTTGCGAGCATTTCCGAGCTCAAGAAAAACCCCATGGGCACCGTTGCGGCCGG
TGGCGGTTCCTCCGTGGCCATCCTCAATCGCAACGAACCGGCGTTTTACTGCGTTCCGGCCAAGGAATACGAAGCCATGA
TGGAGCGTCTGGAAGATATGGAGCTGCTCGCCTTGTGCCGTGAGCGAGAGAATGATTCGACCATCAAGGTTTCGCTCGAT
GACTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References