Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 2389878..2390463 | Replicon | chromosome |
Accession | NZ_CP027739 | ||
Organism | Pseudomonas chlororaphis subsp. piscium strain ToZa7 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | A0A3G7C0N8 |
Locus tag | C4K30_RS10915 | Protein ID | WP_025804099.1 |
Coordinates | 2390170..2390463 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A3G7CJP2 |
Locus tag | C4K30_RS10910 | Protein ID | WP_025804100.1 |
Coordinates | 2389878..2390168 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C4K30_RS10895 | 2385203..2387683 | + | 2481 | WP_063430875.1 | FtsX-like permease family protein | - |
C4K30_RS10900 | 2387673..2388749 | + | 1077 | WP_063429487.1 | iron ABC transporter permease | - |
C4K30_RS10905 | 2388877..2389464 | + | 588 | WP_063429489.1 | hypothetical protein | - |
C4K30_RS10910 | 2389878..2390168 | - | 291 | WP_025804100.1 | putative addiction module antidote protein | Antitoxin |
C4K30_RS10915 | 2390170..2390463 | - | 294 | WP_025804099.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
C4K30_RS10920 | 2390699..2392093 | - | 1395 | WP_063429491.1 | VOC family protein | - |
C4K30_RS10925 | 2392356..2393480 | + | 1125 | WP_051519186.1 | diguanylate cyclase | - |
C4K30_RS10930 | 2393574..2394818 | + | 1245 | WP_025804096.1 | M20/M25/M40 family metallo-hydrolase | - |
C4K30_RS10935 | 2395019..2395417 | + | 399 | WP_025804095.1 | carboxymuconolactone decarboxylase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 10837.49 Da Isoelectric Point: 10.7289
>T100105 WP_025804099.1 NZ_CP027739:c2390463-2390170 [Pseudomonas chlororaphis subsp. piscium]
MEYEILQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNRGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF
MEYEILQTTVFAQWHTRLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNRGAGYRIYFTVRGNTLIVLLLGGDK
STQPADICQARSLAKEF
Download Length: 294 bp
>T100105 NZ_CP027739:c2390463-2390170 [Pseudomonas chlororaphis subsp. piscium]
ATGGAATACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCAGACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATAGGGGCGCCGGCTACCGCATCTATTTCACGGTTCGCGGCAACACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
ATGGAATACGAGATCCTGCAGACGACCGTCTTTGCCCAATGGCACACCAGACTACGGGACCTGCGCGCCAGGATAGCCAT
CGCTCGGCGTATCGAGCGGGCTTCGGCGGGCAACCTGGGCGATGTGAAAAACCTCGGCGGCGGTCTCTCGGAAATGCGCG
TGAATAGGGGCGCCGGCTACCGCATCTATTTCACGGTTCGCGGCAACACCCTCATCGTCCTGCTGCTGGGCGGCGACAAG
TCCACCCAGCCTGCCGATATCTGCCAGGCCCGTTCCCTGGCCAAGGAGTTCTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10249.81 Da Isoelectric Point: 8.0096
>AT100105 WP_025804100.1 NZ_CP027739:c2390168-2389878 [Pseudomonas chlororaphis subsp. piscium]
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVPRG
Download Length: 291 bp
>AT100105 NZ_CP027739:c2390168-2389878 [Pseudomonas chlororaphis subsp. piscium]
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCCTTTGCCCCGGGCGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGTTGTGCACCACAGTGCCCCGAGGCTGA
ATGTCCGACACACTGGTTCCCTTCGACATCGCCACCCTGCTCGACAGCGACCAGGCGATCAGCGAATACCTGTCCCAGGT
CCTGGCCGATGGCGATACCGATGAACTGATCCGCGCCCTGGGCCATGTCGCCAGGGCCCGGGGCATGACGCAGATTGCCA
AGGCCACCGGCCAGGGCCGGGCCAGCCTCTACAAGGCCTTTGCCCCGGGCGCCAAGCCGCGCTTCGATACCGTGGTCAAG
GTCATGCGCGCGCTGGGCCTGCAGTTGTGCACCACAGTGCCCCGAGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G7C0N8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G7CJP2 |